What do systematic reviews say?

Intervention vs control

It is very uncertain whether intervention changes serious adverse events ‐ Recombinant factor VIIa (rFVIIa) versus… compared with control (very low certainty).

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  RR 1.3 [0.94, 1.78]
  2 studies · 266 participants
  Very low

Intervention vs control

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 195 participants
  Very low

Intervention vs control

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 65 participants
  Very low

Intervention vs control

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 62 participants
  Very low

Intervention vs control

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 71 participants
  Very low

Intervention vs control

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 375 participants
  Very low
• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 159 participants
  Very low
• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 221 participants
  Very low

Intervention vs control

It is very uncertain whether intervention changes 60‐day mortality ‐ Tranexamic acid versus control compared with control (very low certainty).

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  RR 0.55 [0.17, 1.76]
  3 studies · 139 participants
  Very low

Intervention vs control

It is very uncertain whether intervention changes 60‐day mortality ‐ Recombinant factor VIIa (rFVIIa) versus control compared with control (very low certainty).

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  RR 1.51 [0.33, 6.95]
  3 studies · 286 participants
  Very low

Intervention vs control

It is very uncertain whether intervention changes 60‐day mortality ‐ Tranexamic acid versus aprotinin compared with control (very low certainty).

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  RR 4.12 [0.71, 23.76]
  2 studies · 178 participants
  Very low

Intervention vs control

It is very uncertain whether intervention changes primary graft non‐function ‐ Aprotinin versus control compared with control (very low certainty).

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  RR 0.15 [0.02, 1.25]
  2 studies · 217 participants
  Very low

Intervention vs control

It is very uncertain whether intervention changes retransplantation ‐ Aprotinin versus control compared with control (very low certainty).

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  RR 0.21 [0.02, 1.79]
  2 studies · 217 participants
  Very low

Intervention vs control

It is very uncertain whether intervention changes retransplantation ‐ Tranexamic acid versus control compared with control (very low certainty).

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  RR 0.79 [0.18, 3.48]
  2 studies · 77 participants
  Very low

Intervention vs control

It is very uncertain whether intervention changes thromboembolic episodes ‐ Aprotinin versus control compared with control (very low certainty).

• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  RR 0.6 [0.18, 1.96]
  3 studies · 280 participants
  Very low
• Methods to decrease blood loss and transfusion requirements for liver transplantation 2011 · Cochrane Headline outcomes only
  RR 2.2 [0.38, 12.64]
  5 studies · 179 participants
  Very low