Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

781 questions · 829 findings · 43 reviews · Headline outcomes only

No studies found 215 · 25.9%GRADE not reported 39 · 4.7%Very low 205 · 24.7%Low 208 · 25.1%Moderate 130 · 15.7%High 32 · 3.9%

Lay health worker‐led psychosocial interventions vs enhanced usual care

Service utilisation ‐ maternal or child hospitalisations ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

It is very uncertain whether lay health worker‐led psychosocial interventions changes service utilisation ‐ maternal or child hospitalisations ‐… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs usual or enhanced care

Depressive symptoms · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes depression symptoms ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs usual or enhanced care

Quality of life ‐ intermediate term (1 to 6 months post intervention) SF‐36 social functioning (higher score = higher quality of life) · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes quality of life ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Severity of CMD symptoms (including anxiety and depression) ‐ intermediate term (1 to 6 months post intervention) Measured by PHQ‐9a,d,f; SRQ‐20b (higher score, higher severity) · adults with common mental disorders
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

PTS symptoms ‐ intermediate term (1 to 6 months post intervention) PCL‐5a,d,e; PCL‐6f; Post‐traumatic Stress Diagnostic Scaleb (higher score = higher severity) · adults with post‐traumatic stress and CMDs
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Depression symptoms ‐ intermediate term (1 to 6 months post intervention) GHQ‐12a; PHQ‐9d,e,f; self‐reporting questionnaireh (higher score = higher severity) · adults with post‐traumatic stress and CMDs
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Quality of life ‐ intermediate term (1 to 6 months post intervention) EQ‐5Di; SF‐36c,m; WHOQOL‐BREFe,j,n (higher score = better quality of life) · adults with post‐traumatic stress and CMDs
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Hospital admissions · adults with post‐traumatic stress and CMDs

It is very uncertain whether lay health worker‐led psychological interventions changes service utilisation ‐ hospital admissions (1 to 6 months post… compared with usual care (very low certainty).

1 finding from 1 review

Primary health professional‐led psychological interventions vs usual care or no treatment

Severity of PTSD symptoms · adults with post‐traumatic stress or common mental disorders

It is very uncertain whether primary health professional‐led psychological interventions changes PTS symptoms (1 to 6 months post intervention) Harvard Trauma… compared with usual or no care (very low certainty).

1 finding from 1 review