Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

451 questions · 479 findings · 42 reviews · Stroke

No studies found 147 · 30.7%GRADE not reported 22 · 4.6%Very low 130 · 27.1%Low 103 · 21.5%Moderate 60 · 12.5%High 17 · 3.5%

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

Functional independence · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in functional independence at 3 months (mRS 0 to 2) (primary outcome) compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

Successful reperfusion (mTICI 2b to 3) postprocedure · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in successful reperfusion (mTICI 2b to 3) postprocedure compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

All‐cause mortality within 3 months · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in all‐cause mortality within 3 months compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

Intracranial hemorrhage on imaging at 24 hours · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in intracranial hemorrhage on imaging at 24 hours compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

Symptomatic intracranial haemorrhage at · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in symptomatic intracranial hemorrhage at 24 hours compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

Procedure‐related adverse events within 3 months · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in procedure‐related adverse events within 3 months compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Prism adaptation training vs control

Neglect outcomes: immediate effects · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether prism adaptation training changes neglect outcomes: immediate effects compared with any control (very low certainty).

1 finding from 1 review