Enamel matrix derivative (EMD) vs Calcium hydroxide (CH)
- Direct pulp capping; overall failure RR 1.00 (0.06 to 15.50) at 6/12 months (Garrocho-Rangel 2009); no pain/soft tissue/mobility/root resorption1 study · 90 participantsGRADE not reported
Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl) showed no clear difference in radiological failure compared with calcium hydroxide + sodium hypochlorite (NaOCl); GRADE not reported.
It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with calcium hydroxide (CH) (very low certainty).
It is very uncertain whether non-rinse conditioner + acetone-based total-etch adhesive changes radiological failure compared with calcium hydroxide (CH) (very low certainty).
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with calcium hydroxide (CH) (very low certainty).
Low-level laser therapy (LLLT) showed no clear difference in radiological failure compared with low-level laser therapy (LLLT) + calcium hydroxide; GRADE not reported.
Mineral trioxide aggregate (MTA) probably leads to lower clinical failure compared with calcium hydroxide (CH) (moderate certainty).
Zinc oxide and eugenol (ZOE) led to lower clinical failure compared with ZOE + calcium hydroxide + iodoform (unnamed product); GRADE not reported.
Low-level laser therapy (LLLT) showed no clear difference in radiological failure compared with calcium hydroxide (CH); GRADE not reported.
The review found no eligible studies for this question.
Erbium:YAG laser showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.
Erbium:YAG laser led to lower radiological failure compared with calcium hydroxide (CH); GRADE not reported.
It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes clinical failure compared with calcium hydroxide (CH) (very low certainty).
Summary of findings: Sevelamer may leads to lower death (all causes) compared with calcium (low certainty).
It is very uncertain whether summary of findings: Sevelamer changes cardiovascular death compared with calcium (very low certainty).
It is very uncertain whether summary of findings: Sevelamer changes hypercalcaemia compared with calcium (very low certainty).