Findings

What do systematic reviews say?

370 questions · 377 findings · 26 reviews · Gut

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No studies found 103 · 27.3%GRADE not reported 11 · 2.9%Very low 99 · 26.3%Low 75 · 19.9%Moderate 67 · 17.8%High 22 · 5.8%

Metronidazole vs budesonide enema

Clinical remission · Patients with acute pouchitis

It is very uncertain whether metronidazole changes clinical remission compared with budesonide enema (very low certainty).

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
RR 0.86 [0.37, 1.96]
1 study · 26 participants
Very low

Adalimumab vs placebo

Adverse events · Patients with ileal pouch‐anal anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Clostridium probiotic vs placebo

Clinical remission · Patients with ileal pouch‐anal anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Clostridium probiotic vs placebo

Clinical improvement · Patients with ileal pouch‐anal anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Clostridium probiotic vs placebo

Maintenance of clinical remission · Patients with ileal pouch‐anal anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Clostridium probiotic vs placebo

No of episodes of acute pouchitis · Patients with ileal pouch‐anal anastomosis

It is very uncertain whether clostridium probiotic changes no of episodes of acute pouchitis compared with placebo (very low certainty).

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
RR 0.22 [0.03, 1.6]
1 study · 17 participants
Very low

Clostridium probiotic vs placebo

Adverse events · Patients with ileal pouch‐anal anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Metronidazole vs budesonide enema

Clinical improvement · Patients with acute pouchitis

It is very uncertain whether metronidazole changes clinical improvement compared with budesonide enema (very low certainty).

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
RR 0.86 [0.42, 1.74]
1 study · 26 participants
Very low

Metronidazole vs budesonide enema

Maintenance of clinical remission · Patients with acute pouchitis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Metronidazole vs budesonide enema

No episodes of acute pouchitis · Patients with acute pouchitis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found