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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

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No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Fecal microbiota transplantation vs control

Serious adverse events · adults with recurrent Clostridioides difficile infection (rCDI)

Summary of findings table ‐ Fecal microbiota transplantation (FMT) showed no clear difference in serious adverse events compared with control (moderate certainty).

1 finding from 1 review

Fecal microbiota transplantation vs control

All‐cause mortality · adults with recurrent Clostridioides difficile infection (rCDI)

Summary of findings table ‐ Fecal microbiota transplantation (FMT) showed no clear difference in all‐cause mortality compared with control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Newly‐diagnosed EOC: PARPi monotherapy vs placebo (maintenance therapy)

Adverse events (grade ≥ 3) · newly‐diagnosed EOC

It is very uncertain whether summary of findings table ‐ Newly‐diagnosed EOC: PARPi monotherapy changes any severe adverse event (grade 3 or higher) (G3+ SevAE ) compared with placebo (maintenance therapy) (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Newly‐diagnosed EOC: PARPi monotherapy vs placebo (maintenance therapy)

Overall survival (OS) · newly‐diagnosed EOC

Summary of findings table ‐ Newly‐diagnosed EOC: PARPi monotherapy showed no clear difference in overall survival (OS) compared with placebo (maintenance therapy) (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Newly‐diagnosed EOC: PARPi monotherapy vs placebo (maintenance therapy)

Progression‐free survival · newly‐diagnosed EOC

Summary of findings table ‐ Newly‐diagnosed EOC: PARPi monotherapy may leads to lower progression‐free survival (PFS) compared with placebo (maintenance therapy) (low certainty).

1 finding from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Change in weight (kg) · overweight and obese participants without T2DM (weight‐reducing phase only)
2 findings from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Weight loss of at least 5% at ≥ 12 months ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Cardiovascular mortality ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

LDL cholesterol (mmol/L), change from baseline · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)
1 finding from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Constipation at 3 to < 12 months ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Change in weight (kg) · overweight and obese participants with T2DM (weight‐reducing phase only)
2 findings from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Weight loss of at least 5% at ≥ 12 months ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase only)

It is very uncertain whether summary of findings table ‐ Low‐carbohydrate weight‐reducing diets changes weight loss of at least 5% at ≥ 12 months compared with balanced‐carbohydrate weight‐reducing diets (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Cardiovascular mortality ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase only)

The review found no eligible studies for this question.

1 finding from 1 review