Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings: Picture Exchange Communication System (PECS) vs treatment

Spoken communication Measured by: frequency of speech, including non‐word vocalisations (expressed as rates per minute)a · minimally verbal children with autism spectrum disorder

It is very uncertain whether summary of findings: Picture Exchange Communication System (PECS) changes spoken communication Measured by: frequency of speech, including… compared with treatment (very low certainty).

1 finding from 1 review

Summary of findings: Picture Exchange Communication System (PECS) vs treatment

Non‐verbal communication/AAC Measured by: frequency of use of PECS symbols (expressed as rates per minute)a · minimally verbal children with autism spectrum disorder

It is very uncertain whether summary of findings: Picture Exchange Communication System (PECS) changes non‐verbal communication/AAC Measured by: frequency of use of PECS… compared with treatment (very low certainty).

1 finding from 1 review

Summary of findings: Picture Exchange Communication System (PECS) vs treatment

Combined spoken and non‐verbal communication/AAC · minimally verbal children with autism spectrum disorder

It is very uncertain whether summary of findings: Picture Exchange Communication System (PECS) changes combined spoken and non‐verbal communication/AAC Measured by: verbal… compared with treatment (very low certainty).

1 finding from 1 review

Summary of findings: Picture Exchange Communication System (PECS) vs treatment

Social communication and pragmatic language skills · minimally verbal children with autism spectrum disorder

It is very uncertain whether summary of findings: Picture Exchange Communication System (PECS) changes social communication or pragmatic language Measured by: reciprocal… compared with treatment (very low certainty).

1 finding from 1 review

Summary of findings: Molecular‐targeted therapy plus chemotherapy vs chemotherapy alone

Progression‐free survival · people with advanced gastric cancer

Summary of findings: Molecular‐targeted therapy plus chemotherapy showed no clear difference in progression‐free survival compared with chemotherapy alone (low certainty).

1 finding from 1 review