Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,749 questions · 14,273 findings · 834 reviews

No studies found 3,655 · 25.6%GRADE not reported 2,115 · 14.8%Very low 3,646 · 25.5%Low 3,034 · 21.3%Moderate 1,503 · 10.5%High 320 · 2.2%

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Primary‐level worker‐led collaborative care vs usual care

Prevalence of CMD ‐ intermediate term (1 to 6 months post intervention) Diagnosis defined by presence of ICD‐10 diagnosis on CIS‐Rg; prevalence defined by [Total number ‐ number recovered (recovery defined by HDRS < 8)]c (RR < 1 denotes lower prev... · adults with common mental disorders

Primary‐level worker‐led collaborative care showed no clear difference in prevalence of CMD ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs specialist‐led care

Hospital admission/re‐admission · people with severe mental disorders

It is very uncertain whether primary health professional‐led or collaborative care changes service utilisation ‐ hospital re‐admission (during intervention)… compared with specialist‐led care (very low certainty).

1 finding from 1 review

Percutaneous patellar osteosynthesis vs open surgery

Observer‐rated measures of knee function Knee function scores (see comment) · adults with fractures of the patella

It is very uncertain whether percutaneous patellar osteosynthesis changes observer‐rated measures of knee function Knee function scores (see… compared with open surgery (very low certainty).

1 finding from 1 review

Pegloticase every two weeks (biweekly) vs placebo

Proportion with complete resolution of a target tophus · participants with tophi in gout

Pegloticase every two weeks (biweekly) probably leads to higher proportion with complete resolution of tophi compared with placebo (moderate certainty).

1 finding from 1 review