Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
Sodium bicarbonate rinse (plus toothbrushing) showed no clear difference in incidence of VAP compared with water rinse (plus toothbrushing); GRADE not reported.
1 finding from 1 review
Periodontitis (probing pocket depth) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)
Clinical examination with 24-month recall showed no clear difference in periodontal disease: probing pocket depth (mm) compared with clinical examination with 6-month recall (moderate certainty).
1 finding from 1 review
Duration of mechanical ventilation · Critically ill patients receiving mechanical ventilation in ICU
Saline rinse showed no clear difference in duration of mechanical ventilation compared with usual care (no rinse); GRADE not reported.
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
Triclosan rinse showed no clear difference in incidence of VAP compared with saline rinse; GRADE not reported.
1 finding from 1 review
Cost (healthcare-system perspective): total cost per patient (GBP) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)
Clinical examination with risk-based recall showed no clear difference in cost (healthcare-system perspective): total cost per patient (GBP) compared with clinical examination with 6-month recall; GRADE not reported.
1 finding from 1 review
Cost (patient perspective): total cost per patient (GBP) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)
Clinical examination with risk-based recall showed no clear difference in cost (patient perspective): total cost per patient (GBP) compared with clinical examination with 6-month recall; GRADE not reported.
1 finding from 1 review
Dental caries: dmfs increment (primary teeth) · Regular-attending primary-care dental patients aged 3, 16 or 18 years at entry (aged up to 20; low caries risk)
It is very uncertain whether clinical examination with 24-month recall changes dental caries: dmfs increment (primary teeth) compared with clinical examination with 12-month recall (very low certainty).
1 finding from 1 review
Cost (healthcare-system perspective): total cost per patient (GBP) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)
Clinical examination with 24-month recall showed no clear difference in cost (healthcare-system perspective): total cost per patient (GBP) compared with clinical examination with 6-month recall; GRADE not reported.
1 finding from 1 review
Development of >=1 new carious lesion (caries incidence) · Patients with drooling (sialorrhea) due to neurological disease
In one RCT, BoNT-B 2500 U was not associated with a statistically significant increase in new caries versus placebo (RR 2.4, 95% CI 0.48 to 11.80; not significant).
2 findings from 1 review
Periodontitis (probing pocket depth) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)
Clinical examination with risk-based recall probably leads to higher periodontal disease: probing pocket depth (mm) compared with clinical examination with 24-month recall (moderate certainty).
1 finding from 1 review
Patient satisfaction with actual care received (1-7 scale) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)
Clinical examination with risk-based recall led to higher patient satisfaction with actual care received (1-7 scale) compared with clinical examination with 24-month recall; GRADE not reported.
1 finding from 1 review
Periodontitis (probing pocket depth) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)
Clinical examination with risk-based recall showed no clear difference in periodontal disease: probing pocket depth (mm) compared with clinical examination with 6-month recall (high certainty).
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Failure to induce global or clinical remission · Patients with active mild to moderate ulcerative colitis
Once daily dosing showed no clear difference in failure to induce global or clinical remission compared with conventional dosing (high certainty).
1 finding from 1 review
Failure to induce global or clinical improvement · Patients with active mild to moderate ulcerative colitis
Once daily dosing showed no clear difference in failure to induce global or clinical improvement compared with conventional dosing (moderate certainty).
1 finding from 1 review
Failure to induce endoscopic remission · Patients with active mild to moderate ulcerative colitis
Once daily dosing showed no clear difference in failure to induce endoscopic remission compared with conventional dosing (high certainty).
1 finding from 1 review
Failure to adhere to medication regimen · Patients with active mild to moderate ulcerative colitis
Once daily dosing showed no clear difference in failure to adhere to medication regimen compared with conventional dosing (low certainty).
1 finding from 1 review
Adverse events · Patients with active mild to moderate ulcerative colitis
Once daily dosing showed no clear difference in adverse events compared with conventional dosing (moderate certainty).
1 finding from 1 review
Serious adverse events · Patients with active mild to moderate ulcerative colitis
Once daily dosing showed no clear difference in serious adverse events compared with conventional dosing (low certainty).
1 finding from 1 review