Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Wavefront‐guided LASIK vs wavefront‐guided PRK

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Loss of 1 or more lines of BSCVA at 12 months post treatment · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes that had lost 1 or more lines of best… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront‐guided LASIK vs wavefront‐guided PRK

Eyes within ± 0.5 D of target refraction · Adults with refractive errors

It is very uncertain whether wavefront‐guided LASIK changes proportion of eyes within ± 0.50 diopters (D) of target refraction… compared with wavefront‐guided PRK (very low certainty).

1 finding from 1 review

Wavefront procedures vs conventional procedures

Proportion of eyes that had lost 1 or more lines of best spectacle‐corrected visual acuity (BSCVA) posttreatment:12 months ‐ Procedure PRK · Adults with refractive errors

Wavefront procedures showed no clear difference in proportion of eyes that had lost 1 or more lines of best… compared with conventional procedures (low certainty).

1 finding from 1 review

Wavefront procedures vs conventional procedures

Proportion of eyes within ± 0.50 diopters (D) of target refraction: 12 months ‐ Procedure PRK · Adults with refractive errors

Wavefront procedures showed no clear difference in proportion of eyes within ± 0.50 diopters (D) of target refraction:… compared with conventional procedures (low certainty).

1 finding from 1 review

Wavefront procedures vs conventional procedures

Proportion of eyes that had lost 1 or more lines of best spectacle‐corrected visual acuity (BSCVA) posttreatment‐procedure LASIK; Mean higher‐order aberrations (HOAs) post‐treatment, measured by machine with wavefront sensor; proportion of eyes wi... · Adults with refractive errors

The review found no eligible studies for this question.

1 finding from 1 review

Wavefront‐optimized procedures vs wavefront‐guided procedures

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

Wavefront‐optimized procedures showed no clear difference in proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with wavefront‐guided procedures (low certainty).

1 finding from 1 review

Wavefront‐optimized procedures vs wavefront‐guided procedures

Loss of 1 or more lines of BSCVA at 12 months post treatment · Adults with refractive errors

Wavefront‐optimized procedures showed no clear difference in proportion of eyes that had lost 1 or more lines of best… compared with wavefront‐guided procedures (low certainty).

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Glaucoma progression at 12 months, measured by additional visual field defects · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Mean change in health‐related quality of life · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review