Intervention not reported
Lamotrigine · adults and children with focal seizures
1 finding from 1 review
Intervention not reported
Comparison (reference treatment) · adults and children with generalised seizures*
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Sodium valproate · adults and children with generalised seizures*
1 finding from 1 review
Intervention not reported
Adverse events · adults and children with focal seizures
1 finding from 1 review
Intervention not reported
Lack of efficacy · adults and children with focal seizures
1 finding from 1 review
Intervention not reported
Any reason · adults and children with focal seizures
1 finding from 1 review
Intervention not reported
Adverse events · adults and children with focal seizures
1 finding from 1 review
Intervention not reported
Lack of efficacy · adults and children with focal seizures
1 finding from 1 review
Intervention not reported
Any reason · adults and children with generalised tonic‐clonic seizures with or without other seizure types
1 finding from 1 review
Intervention not reported
Adverse events · adults and children with generalised tonic‐clonic seizures with or without other seizure types
1 finding from 1 review
Intervention not reported
Lack of efficacy · adults and children with generalised tonic‐clonic seizures with or without other seizure types
1 finding from 1 review
50% or greater reduction in seizure frequency · people with drug‐resistant focal epilepsy
Brivaracetam probably leads to higher 50% or greater reduction in seizure frequency (responder rate) compared with placebo (moderate certainty).
1 finding from 1 review
Seizure freedom · people with drug‐resistant focal epilepsy
Brivaracetam may leads to higher seizure freedom compared with placebo (low certainty).
1 finding from 1 review
Treatment withdrawal · people with drug‐resistant focal epilepsy
Brivaracetam showed no clear difference in treatment withdrawal compared with placebo (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with drug‐resistant focal epilepsy
Brivaracetam may leads to higher proportion of participants who experienced adverse events leading to… compared with placebo (low certainty).
1 finding from 1 review
Adverse events as N of participants with at least one adverse event objective · people with drug‐resistant focal epilepsy
Brivaracetam showed no clear difference in proportion of participants who experienced any adverse events compared with placebo (moderate certainty).
1 finding from 1 review
Survival ‐ · adults (aged 18+) with colorectal cancer
Adjunctive Coriolus versicolor may leads to higher survival ‐ compared with no adjunctive treatment (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · adults (aged 18+) with colorectal cancer
It is very uncertain whether adjunctive Coriolus versicolor changes withdrawal from treatment due to adverse events ‐ compared with no adjunctive treatment (very low certainty).
1 finding from 1 review
Adverse events: Oral cavity disorders (includes oral dryness and mucositis)‐ · adults (aged 18+) with colorectal cancer
It is very uncertain whether adjunctive Coriolus versicolor changes adverse events: Oral cavity disorders (includes oral dryness and… compared with no adjunctive treatment (very low certainty).
1 finding from 1 review
Adverse events: nausea · adults (aged 18+) with colorectal cancer
It is very uncertain whether adjunctive Coriolus versicolor changes adverse events: Nausea ‐ compared with no adjunctive treatment (very low certainty).
1 finding from 1 review