Findings

What do systematic reviews say?

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

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No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Laparoscopic treatment vs diagnostic laparoscopy

Overall pain scores unclear measurement instrument (12 months) · women with endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Laparoscopic treatment vs diagnostic laparoscopy

Live birth · women with endometriosis

The review found no eligible studies for this question.

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laparoscopic treatment vs diagnostic laparoscopy

Quality of life EQ‐5D index summary (6 months) · women with endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Laparoscopic treatment vs diagnostic laparoscopy

Health‐related quality of life (mental) · women with endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Laparoscopic treatment vs diagnostic laparoscopy

Health‐related quality of life (physical) · women with endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Laparoscopic treatment vs diagnostic laparoscopy

Viable intrauterine Pregnancy · women with endometriosis

Laparoscopic treatment probably leads to higher viable intrauterine pregnancy confirmed by ultrasound compared with diagnostic laparoscopy (moderate certainty).

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
OR 1.89 [1.25, 2.86]
3 studies · 528 participants
Moderate

Laparoscopic treatment vs diagnostic laparoscopy

Pregnancy loss: ectopic pregnancy per pregnancy · women with endometriosis

Laparoscopic treatment showed no clear difference in pregnancy loss: ectopic pregnancy per pregnancy compared with diagnostic laparoscopy (low certainty).

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
OR 1.18 [0.1, 13.48]
1 study · 100 participants
Low

Laparoscopic treatment vs diagnostic laparoscopy

Miscarriage pregnancy rate · women with endometriosis

Laparoscopic treatment showed no clear difference in pregnancy loss: miscarriage per pregnancy compared with diagnostic laparoscopy (low certainty).

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
OR 0.94 [0.35, 2.54]
2 studies · 112 participants
Low

Hormone replacement therapy (HRT) vs no HRT

Overall survival

Hormone replacement therapy (HRT) may leads to lower overall survival compared with no HRT (low certainty).

1 finding from 1 review

Hormone replacement therapy after surgery for epithelial ovarian cancer 2020 · Cochrane Headline outcomes only
HR 0.71 [0.54, 0.93]
3 studies · 350 participants
Low

Hormone replacement therapy (HRT) vs no HRT

Quality of life: 1. General quality of life

1 finding from 1 review

Hormone replacement therapy after surgery for epithelial ovarian cancer 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 75 participants
Very low

Hormone replacement therapy (HRT) vs no HRT

Progression‐free survival

Hormone replacement therapy (HRT) showed no clear difference in progression‐free survival compared with no HRT (low certainty).

1 finding from 1 review

Hormone replacement therapy after surgery for epithelial ovarian cancer 2020 · Cochrane Headline outcomes only
HR 0.76 [0.57, 1.01]
2 studies · 275 participants
Low

Hormone replacement therapy (HRT) vs no HRT

Overall breast cancer incidence

It is very uncertain whether hormone replacement therapy (HRT) changes incidence of breast cancer compared with no HRT (very low certainty).

1 finding from 1 review

Hormone replacement therapy after surgery for epithelial ovarian cancer 2020 · Cochrane Headline outcomes only
RR 2 [0.19, 21.59]
2 studies · 225 participants
Very low

Hormone replacement therapy (HRT) vs no HRT

Incidence of transient ischaemic attack

It is very uncertain whether hormone replacement therapy (HRT) changes incidence of transient ischaemic attack compared with no HRT (very low certainty).

1 finding from 1 review

Hormone replacement therapy after surgery for epithelial ovarian cancer 2020 · Cochrane Headline outcomes only
RR 5 [0.24, 102.42]
1 study · 150 participants
Very low

Hormone replacement therapy (HRT) vs no HRT

Incidence of cerebrovascular accident

It is very uncertain whether hormone replacement therapy (HRT) changes incidence of cerebrovascular accident compared with no HRT (very low certainty).

1 finding from 1 review

Hormone replacement therapy after surgery for epithelial ovarian cancer 2020 · Cochrane Headline outcomes only
RR 0.67 [0.11, 3.88]
1 study · 150 participants
Very low

Hormone replacement therapy (HRT) vs no HRT

Myocardial infarction

It is very uncertain whether hormone replacement therapy (HRT) changes incidence of myocardial infarction compared with no HRT (very low certainty).

1 finding from 1 review

Hormone replacement therapy after surgery for epithelial ovarian cancer 2020 · Cochrane Headline outcomes only
RR 0.2 [0.01, 4.1]
1 study · 150 participants
Very low

Hormone replacement therapy (HRT) vs no HRT

Incidence of gallstones

The review found no eligible studies for this question.

1 finding from 1 review

Hormone replacement therapy after surgery for epithelial ovarian cancer 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Wavefront procedures vs conventional procedures

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · Adults with refractive errors

Wavefront procedures showed no clear difference in proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or… compared with conventional procedures (low certainty).

1 finding from 1 review

Wavefront excimer laser refractive surgery for adults with refractive errors 2020 · Cochrane Headline outcomes only
RR 1.03 [0.86, 1.24]
1 study · 70 participants
Low

Wavefront‐optimized procedures vs wavefront‐guided procedures

Eyes within ± 0.5 D of target refraction · Adults with refractive errors

Wavefront‐optimized procedures showed no clear difference in proportion of eyes within ± 0.50 diopters (D) of target refraction… compared with wavefront‐guided procedures (low certainty).

1 finding from 1 review

Wavefront excimer laser refractive surgery for adults with refractive errors 2020 · Cochrane Headline outcomes only
RR 1.02 [0.95, 1.09]
4 studies · 480 participants
Low

Wavefront‐optimized procedures vs wavefront‐guided procedures

Mean refractive error expressed as mean spherical equivalent post‐treatment:12 months ‐ Procedure PRK · Adults with refractive errors

1 finding from 1 review

Wavefront excimer laser refractive surgery for adults with refractive errors 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 334 participants
Low

Wavefront‐optimized procedures vs wavefront‐guided procedures

Mean refractive error expressed as mean spherical equivalent post‐treatment. ‐ 12 months · Adults with refractive errors

1 finding from 1 review

Wavefront excimer laser refractive surgery for adults with refractive errors 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 472 participants
Low