Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

3,601 questions in 252 reviews · Pregnancy and Childbirth

current versions
No studies 726 · 20.2%Ungraded 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal pain within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 74 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal pain 24 ‐ 48 hours after giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 1.21 [0.89, 1.65]2 studies · 263 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal pain 24 ‐ 48 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 74 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal oedema within 4 ‐ 6 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 1.39 [0.93, 2.09]1 study · 49 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal oedema within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.97 [0.84, 1.13]2 studies · 264 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal oedema 24 ‐ 48 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 1.69 [1.03, 2.77]2 studies · 264 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal bruising within 4 ‐ 6 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 1.23 [0.51, 2.97]1 study · 49 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal bruising within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.95 [0.79, 1.14]2 studies · 264 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal redness, oedema, bruising, discharge, wound gaping within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 74 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Adverse effects on perineal wound healing: Day 5 ‐ Wound not healing · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 1.01 [0.26, 3.93]1 study · 215 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Perineal pain between 24 ‐ 48 after giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.73 [0.57, 0.94]1 study · 316 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Adverse effects on perineal wound healing: Day 5 ‐ Wound edges gaping · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.22 [0.05, 1.01]1 study · 215 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Maternal views and experiences with treatment ‐ Opinion on treatment effects (good + very good + excellent) Day 5 · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.33 [0.17, 0.68]1 study · 49 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Maternal views and experiences with treatment ‐ Satisfaction with overall perineal care (good + very good + excellent) Day 10 · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.82 [0.73, 0.92]1 study · 208 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Perineal pain 24 ‐ 48 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 71 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Perineal oedema within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 1 [0.87, 1.16]1 study · 316 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Perineal bruising within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.98 [0.81, 1.19]1 study · 316 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Perineal bruising 24 ‐ 48 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 1.13 [0.97, 1.32]1 study · 316 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Perineal redness, oedema, bruising, discharge, wound gaping 24 ‐ 48 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 71 participantsVery low
Cabbage leaf treatments vs other treatments/placebo
Breast pain · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted4 studies · 393 participantsVery low
Compress treatments vs other treatments/routine care
Breast swelling · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Compress treatments vs other treatments/routine care
Breast engorgement · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted2 studies · 116 participantsVery low
Compress treatments vs other treatments/routine care
Maternal opinion of treatment · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Compress treatments vs other treatments/routine care
Cessation of breastfeeding, · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 102 participantsVery low
Compress treatments vs other treatments/routine care
Number of women with adverse events, · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 500 participantsModerate
Medical treatments vs placebo
Breast pain · women with breast engorgement
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted2 studies · 70 participantsLow
Medical treatments vs placebo
Breast induration/hardness · women with breast engorgement
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Medical treatments vs placebo
Breast swelling · women with breast engorgement
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted2 studies · 129 participantsLow
Medical treatments vs placebo
Breast engorgement, · women with breast engorgement
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted2 studies · 115 participantsLow
Medical treatments vs placebo
Maternal opinion of treatment · women with breast engorgement
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Cabbage leaf treatments vs other treatments/placebo
Breast induration/hardness · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 227 participantsLow
Medical treatments vs placebo
Cessation of breastfeeding · women with breast engorgement
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Medical treatments vs placebo
Number of women with adverse events, · women with breast engorgement
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted2 studies · 129 participantsLow
Cold gel packs vs routine care
Breast pain · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted3 studies · 200 participantsVery low
Cold gel packs vs routine care
Breast induration/hardness · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 151 participantsLow
Cold gel packs vs routine care
Breast swelling · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Cold gel packs vs routine care
Breast engorgement · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Cold gel packs vs routine care
Maternal opinion of treatment, · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 151 participantsLow
Cold gel packs vs routine care
Cessation of breastfeeding, · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 109 participantsLow
Cold gel packs vs routine care
Number of women with adverse events · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Massage‐based therapies vs other treatments/routine care
Breast pain · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 102 participantsLow
Cabbage leaf treatments vs other treatments/placebo
Breast swelling · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Massage‐based therapies vs other treatments/routine care
Breast induration/hardness · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 102 participantsLow
Massage‐based therapies vs other treatments/routine care
Breast swelling · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Massage‐based therapies vs other treatments/routine care
Breast engorgement · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 100 participantsLow
Massage‐based therapies vs other treatments/routine care
Maternal opinion of treatment · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Massage‐based therapies vs other treatments/routine care
Cessation of breastfeeding, · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 152 participantsLow
Massage‐based therapies vs other treatments/routine care
Number of women with adverse events · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies
Other treatments vs other treatments/advice/routine care
Breast pain · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extracted1 study · 54 participantsLow
Other treatments vs other treatments/advice/routine care
Breast induration/hardness · women with breast engorgement during lactation
Treatments for breast engorgement during lactation (2020) · Cochrane
no estimate extractedNRNo studies