Findings

What do systematic reviews say?

416 questions · 426 findings · 56 reviews

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No studies found 109 · 25.6%GRADE not reported 23 · 5.4%Very low 109 · 25.6%Low 106 · 24.9%Moderate 64 · 15%High 15 · 3.5%

Summary of findings for IV fenoterol bromhydrate vs emergency delivery

Abnormal FHR tracing · women with a non‐reassuring fetal heart trace during labour but without uterine tachysystole

The review found no eligible studies for this question.

1 finding from 1 review

Acute tocolysis for uterine tachysystole or suspected fetal distress 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Enoxaparin vs no enoxaparin

Major bleeding · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

1 finding from 1 review

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 224 participants
GRADE not reported

Summary of Findings Table ‐ Enoxaparin vs no enoxaparin

Thrombosis‐related mortality ‐ not reported · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Enoxaparin vs no enoxaparin

Quality of life ‐ not reported · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Enoxaparin vs no enoxaparin

Asymptomatic venous thromboembolism ‐ not reported · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Enoxaparin vs no enoxaparin

Adverse events: clinically relevant non‐major bleeding / heparin‐induced thrombocytopenia ‐ not reported · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Enoxaparin vs no enoxaparin

All‐cause mortality ‐ not reported · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Enoxaparin vs no enoxaparin

First‐time symptomatic venous thromboembolism · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

1 finding from 1 review

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 224 participants
GRADE not reported

Summary of findings table ‐ Remifentanil vs diazepam

Fetal immobilisation score at 40 minutes (Degree of fetal immobilisation as defined by trial authors) · health problem or population

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Fetal movements ‐ gross body and limb (Degree of fetal immobilisation as defined by trial authors) · health problem or population

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Surgical assessment/satisfaction score = 1 or 2 (Technically successful procedure as defined by trial authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to higher surgical assessment/satisfaction score = 1 or 2 (Technically… compared with diazepam (low certainty).

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
RR 2.88 [1.6, 5.15]
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Maternal respiratory rate (Maternal respiratory depression as defined by trial authors or measured using intraoperative maternal arterial oxygen saturation and maternal respiratory rate) · health problem or population

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Maternal OAA score (observer assessment of alertness/sedation) < 4 (Maternal sedation measured using sedation scores as defined by authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to lower maternal OAA score (observer assessment of alertness/sedation) < 4… compared with diazepam (low certainty).

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
RR 0.09 [0.01, 0.65]
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Perinatal mortality · health problem or population

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Remifentanil vs diazepam

Time taken to perform procedure · health problem or population

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intranasal steroid spray vs control

OME resolution at short‐term · Children with otitis media with effusion

Summary of findings: intranasal steroids showed no clear difference in OME resolution at short‐term compared with control (moderate certainty).

1 finding from 1 review

Oral or topical nasal steroids for hearing loss associated with otitis media with effusion in children 2011 · Cochrane Headline outcomes only
RR 0.64 [0.31, 1.31]
1 study · 44 participants
Moderate

Intranasal steroid spray vs control

OME resolution at intermediate‐term · Children with otitis media with effusion

Summary of findings: intranasal steroids showed no clear difference in OME resolution at intermediate‐term compared with control (moderate certainty).

1 finding from 1 review

Oral or topical nasal steroids for hearing loss associated with otitis media with effusion in children 2011 · Cochrane Headline outcomes only
RR 1.11 [0.85, 1.46]
1 study · 172 participants
Moderate

Intranasal steroid spray vs control

OME resolution at long‐term · Children with otitis media with effusion

Summary of findings: intranasal steroids probably leads to lower OME resolution at long‐term compared with control (moderate certainty).

1 finding from 1 review

Oral or topical nasal steroids for hearing loss associated with otitis media with effusion in children 2011 · Cochrane Headline outcomes only
RR 0.85
1 study · 144 participants
Moderate

Intranasal steroid spray vs control

Symptoms · Children with otitis media with effusion

The review found no eligible studies for this question.

1 finding from 1 review

Oral or topical nasal steroids for hearing loss associated with otitis media with effusion in children 2011 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intranasal steroid spray vs control

Adverse effects [3 months] · Children with otitis media with effusion

Summary of findings: intranasal steroids showed no clear difference in adverse effects [3 months] compared with control (low certainty).

1 finding from 1 review

Oral or topical nasal steroids for hearing loss associated with otitis media with effusion in children 2011 · Cochrane Headline outcomes only
RR 1.26 [0.8, 1.99]
2 studies · 231 participants
Low