Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

358 questions · 360 findings · 31 reviews · Vascular

No studies found 86 · 23.9%GRADE not reported 15 · 4.2%Very low 40 · 11.1%Low 117 · 32.5%Moderate 90 · 25%High 12 · 3.3%

Padma 28 vs placebo

Adverse effects · people with symptomatic intermittent claudication

It is very uncertain whether padma 28 changes adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Statins vs placebo

Total VTE · 17,802 patients with low to normal levels of low density lipoprotein (LDL) cholesterol (< 130 mg/dL)

Statin probably leads to lower all cases of VTE compared with placebo (moderate certainty).

1 finding from 1 review

Statins vs placebo

Any MI · 17,802 patients with low to normal levels of low density lipoprotein (LDL) cholesterol (< 130 mg/dL)

Statin probably leads to lower any MI compared with placebo (moderate certainty).

1 finding from 1 review

Statins vs placebo

Stroke · 17,802 patients with low to normal levels of low density lipoprotein (LDL) cholesterol (< 130 mg/dL)

Statin probably leads to lower any stroke compared with placebo (moderate certainty).

1 finding from 1 review

Statins vs placebo

Death · 17,802 patients with low to normal levels of low density lipoprotein (LDL) cholesterol (< 130 mg/dL)

Statin probably leads to lower death compared with placebo (moderate certainty).

1 finding from 1 review

Statins vs placebo

Any serious adverse event · 17,802 patients with low to normal levels of low density lipoprotein (LDL) cholesterol (< 130 mg/dL)

Statin showed no clear difference in any serious adverse event compared with placebo (moderate certainty).

1 finding from 1 review