Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,756 questions · 13,493 findings · 1,305 reviews · Headline outcomes only

No studies found 2,594 · 19.2%GRADE not reported 728 · 5.4%Very low 2,868 · 21.3%Low 3,777 · 28%Moderate 2,620 · 19.4%High 906 · 6.7%

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Summary of findings table ‐ Topical capsaicin vs placebo

Risk for at least one adverse event per patient · patients with chronic kidney disease (CKD) pruritus

Summary of findings table ‐ Topical capsaicin may leads to higher risk for at least one adverse event per patient compared with placebo (low certainty).

1 finding from 1 review

Summary of findings table ‐ Rifampin/rifampicin vs placebo

Risk for at least one adverse event per patient · participants with cholestatic pruritus (CP)

It is very uncertain whether summary of findings table ‐ Rifampin/rifampicin changes risk for at least one adverse event per patient compared with placebo (very low certainty).

1 finding from 1 review

Topical corticosteroids vs placebo or no treatment

Complete resolution of phimosis · boys up to 18 years old with phimosis

Topical corticosteroids may leads to higher complete resolution of phimosis compared with placebo or no treatment (low certainty).

2 findings from 1 review