Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

668 questions · 685 findings · 68 reviews · Headline outcomes only

No studies found 181 · 26.4%GRADE not reported 16 · 2.3%Very low 151 · 22%Low 211 · 30.8%Moderate 98 · 14.3%High 28 · 4.1%

Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziometacarpal joint replacement (Swanson)

Adverse events Complications reported · Patients with thumb (trapeziometacarpal joint) osteoarthritis

Trapeziectomy with interpositional arthroplasty (T and IA) showed no clear difference in adverse events Complications reported compared with trapeziometacarpal joint replacement (Swanson) (low certainty).

1 finding from 1 review

Primary comparison for continuous passive motion (CPM) vs no CPM

Manipulation under anaesthesia · hospitalised patients who have undergone knee replacement surgery

It is very uncertain whether primary comparison for continuous passive motion (CPM) changes manipulation under anaesthesia Counts of manipulation under… compared with no CPM (very low certainty).

1 finding from 1 review

Primary comparison for continuous passive motion (CPM) vs no CPM

Adverse events (a count of reported harms or adverse events/experiences over life of study/ · hospitalised patients who have undergone knee replacement surgery

Primary comparison for continuous passive motion (CPM) showed no clear difference in adverse events Counts of adverse events compared with no CPM (low certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related infectious complications ‐ Catheter colonization · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter colonization compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related blood stream infection · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter related… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related infectious complication ‐ Subgroup Analysis for the effect of BMI on catheter colonization ‐ Highest BMI tercile (>28.4) · critically ill patients who were expected to require support with renal replacement therapy

Femoral probably leads to higher catheter‐related infectious complication ‐ Subgroup Analysis for the… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related thrombotic complications ‐ Symptomatic deep venous thrombosis · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related thrombotic complications ‐ Symptomatic deep venous… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related thrombosis at any time during catheter stay · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related thrombotic complications ‐ Catheter related… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Immediate mechanical complications ‐ Total mechanical complications · critically ill patients who were expected to require support with renal replacement therapy

Femoral probably leads to lower immediate mechanical complications ‐ Total mechanical complications compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review