Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

584 questions · 593 findings · 51 reviews · Airways

No studies found 37 · 6.2%GRADE not reported 40 · 6.7%Very low 44 · 7.4%Low 172 · 29%Moderate 232 · 39.1%High 68 · 11.5%

MgSO4 + SABA vs SABA

Admission to hospital at initial presentation · adults and children with acute exacerbation of asthma

MgSO4 + SABA showed no clear difference in admission to hospital at initial presentation compared with SABA (low certainty).

1 finding from 1 review

MgSO4 vs SABA

Admission to hospital at initial presentation · adults and children with acute exacerbation of asthma

It is very uncertain whether mgSO4 changes admission to hospital at initial presentation compared with SABA (very low certainty).

1 finding from 1 review

Intervention not reported

Patients with ≥ 1 exacerbations requiring oral corticosteroids Duration of trials: 6 to 16 weeks · adults and adolescents with persistent asthma

The intervention probably leads to lower patients with ≥ 1 exacerbations requiring oral corticosteroids… (moderate certainty).

1 finding from 1 review