Findings

What do systematic reviews say?

2,256 questions · 2,339 findings · 262 reviews

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No studies found 555 · 23.7%GRADE not reported 398 · 17%Very low 572 · 24.5%Low 476 · 20.4%Moderate 240 · 10.3%High 98 · 4.2%

Analysis 1 ‐ Oxidised regenerated cellulose vs no treatment at laparotomy

Adhesion score · women having gynaecological surgery

The review found no eligible studies for this question.

1 finding from 1 review

Barrier agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Gel agents vs no gel agents (or placebo)

Mean adhesion score at second‐look laparoscopy · women having gynaecological surgery

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 159 participants
Moderate

Gel agents vs hydroflotation agents used

Incidence of adhesions at second‐look laparoscopy · women during gynaecological surgery

Gel agents probably leads to lower incidence of adhesions at second‐look laparoscopy compared with hydroflotation agents used (moderate certainty).

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
OR 0.5 [0.31, 0.83]
3 studies · 538 participants
Moderate

Gel agents vs hydroflotation agents used

Mean adhesion score at second‐look laparoscopy · women during gynaecological surgery

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 77 participants
Very low

Steroids vs no steroids (or placebo)

Incidence of adhesions at second‐look laparoscopy · women after gynaecological surgery

The review found no eligible studies for this question.

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Steroids vs no steroids (or placebo)

Mean adhesion score at second‐look laparoscopy · women after gynaecological surgery

The review found no eligible studies for this question.

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hydroflotation agents vs no hydroflotation agents (or placebo)

Incidence of adhesions at second‐look laparoscopy · women having gynaecological surgery

Hydroflotation agents leads to lower incidence of adhesions at second‐look laparoscopy compared with no hydroflotation agents (or placebo) (high certainty).

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
OR 0.34 [0.22, 0.55]
4 studies · 566 participants
High

Hydroflotation agents vs no hydroflotation agents (or placebo)

Mean adhesion score at second‐look laparoscopy · women having gynaecological surgery

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 722 participants
Moderate

Gel agents vs no gel agents (or placebo)

Incidence of adhesions at second‐look laparoscopy · women having gynaecological surgery

Gel agents leads to lower incidence of adhesions at second‐look laparoscopy compared with no gel agents (or placebo) (high certainty).

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
OR 0.26 [0.12, 0.57]
5 studies · 147 participants
High

Paracervical vs intravenous diazepam/pethidine analgesia

Requirement of additional analgesia or general anaesthesia · women with persistent or prolonged retention of placenta

The review found no eligible studies for this question.

1 finding from 1 review

Anaesthesia/analgesia for manual removal of retained placenta 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Combined spinal‐epidural vs high‐dose spinal

Number of women requiring intra‐operative conversion to general anaesthesia · women undergoing caesarean section

It is very uncertain whether combined spinal‐epidural changes number of women requiring intra‐operative conversion to general… compared with high‐dose spinal (very low certainty).

1 finding from 1 review

Combined spinal‐epidural versus spinal anaesthesia for caesarean section 2019 · Cochrane Headline outcomes only
RR 1 [0.07, 14.95]
7 studies · 388 participants
Very low

Combined spinal‐epidural vs high‐dose spinal

Number of women satisfied with anaesthesia · women undergoing caesarean section

It is very uncertain whether combined spinal‐epidural changes number of women satisfied with anaesthesia compared with high‐dose spinal (very low certainty).

1 finding from 1 review

Combined spinal‐epidural versus spinal anaesthesia for caesarean section 2019 · Cochrane Headline outcomes only
RR 0.93 [0.73, 1.19]
2 studies · 72 participants
Very low

Combined spinal‐epidural vs low‐dose spinal

Number of women requiring intra‐operative conversion to general anaesthesia · women undergoing caesarean section

1 finding from 1 review

Combined spinal‐epidural versus spinal anaesthesia for caesarean section 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 222 participants
Low

Combined spinal‐epidural vs low‐dose spinal

Number of women satisfied with anaesthesia · women undergoing caesarean section

1 finding from 1 review

Combined spinal‐epidural versus spinal anaesthesia for caesarean section 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Adverse effects of local or regional anaesthesia ‐ not reported · women after caesarean section

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Light-cured resin-modified glass ionomer cement vs Light-cured compomer (polyacid-modified composite resin)

Band failure (band adhesive loosening) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…

1 finding from 1 review

Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
Approximately 12 months (to end of treatment)
Fricker 1997 was a three-arm split-mouth trial that included a light-cured resin-modified glass ionomer arm (compared with light-cured compomer and chemically cured glass ionomer). Failure rates were reported but not…
1 study
GRADE not reported

Chemically cured zinc phosphate cement vs Glass ionomer cement (GIC)

Band failure (band adhesive loosening) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…

1 finding from 1 review

Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
Approximately 12 months (to end of treatment)
No meta-analysis (band failure not reported on a per-patient basis). Durning 1989 (69 participants): at ~12 months failure rate 34.78% (zinc phosphate) vs 26% (glass ionomer), P > 0.05; mean survival time 470.9 vs…
4 studies
GRADE not reported

Chemically cured glass ionomer cement vs Chemically cured glass phosphonate

Band failure (band adhesive loosening) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…

1 finding from 1 review

Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
Approximately 12 months (to end of treatment)
Clark 2003: failure rates presented per adhesive group by number of bands failing (overall proportion of band failure 0.048 for each material); no per-patient failure data. Low band failure rates; insufficient evidence…
1 study
GRADE not reported

Chemically cured glass ionomer cement vs Light-cured compomer (polyacid-modified composite resin)

Band failure (band adhesive loosening) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…

1 finding from 1 review

Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
Approximately 12 months (to end of treatment)
No meta-analysis. Fricker 1997: failure data not presented in an analysable format (number of bands or failures per person not given). Gillgrass 2001 (98 participants; 140 band pairs): 4 single-band failures with…
3 studies
GRADE not reported

Anti‐D administration in pregnancy vs no treatment

Incidence of Rhesus D alloimmunisation during pregnancy · Rh‐negative women without anti‐D antibodies

Anti‐D administration in pregnancy showed no clear difference in incidence of Rhesus D alloimmunisation during pregnancy compared with no treatment (low certainty).

1 finding from 1 review

Anti‐D administration in pregnancy for preventing Rhesus alloimmunisation 2015 · Cochrane Headline outcomes only
RR 0.42 [0.15, 1.17]
2 studies · 3902 participants
Low