Findings

What do systematic reviews say?

344 questions · 346 findings · 97 reviews · Headline outcomes only

No studies found 31 · 9%GRADE not reported 6 · 1.7%Very low 154 · 44.5%Low 99 · 28.6%Moderate 39 · 11.3%High 17 · 4.9%

FEV1 (L) · patients with acute asthma

ICS showed no clear difference in FEV1 at 1 hour compared with placebo (low certainty).

1 finding from 1 review

FEV1 · patients with acute asthma

ICS showed no clear difference in FEV1 at 3 to 4 hours compared with placebo (moderate certainty).

1 finding from 1 review

Nausea and vomiting · patients with acute asthma

ICS showed no clear difference in adverse effects ‐ nausea/vomiting compared with placebo (low certainty).

1 finding from 1 review

Early use of inhaled corticosteroids in the emergency department treatment of acute asthma 2012 · Cochrane Headline outcomes only
OR 0.32 [0.03, 3.18]
1 study · 94 participants
Low

Hospital admissions · patients with acute asthma

ICS showed no clear difference in hospital admission compared with systemic corticosteroids (low certainty).

1 finding from 1 review

Early use of inhaled corticosteroids in the emergency department treatment of acute asthma 2012 · Cochrane Headline outcomes only
OR 0.56 [0.25, 1.24]
10 studies · 763 participants
Low