Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

695 questions · 728 findings · 63 reviews · Headline outcomes only

No studies found 219 · 30.1%GRADE not reported 55 · 7.6%Very low 194 · 26.6%Low 136 · 18.7%Moderate 90 · 12.4%High 34 · 4.7%

Budesonide 10 mg vs prednisolone

Adverse event ‐ Reduction in plasma cortisol below lower reference limit · Adult patients with active ulcerative colitis

It is very uncertain whether budesonide 10 mg changes adverse event ‐ Reduction in plasma cortisol below lower reference… compared with prednisolone 40 mg (very low certainty).

1 finding from 1 review

Budesonide vs mesalamine

Remission (combined clinical and endoscopic remission) · Adult patients with active ulcerative colitis

Budesonide showed no clear difference in remission (combined clinical and endoscopic remission) compared with mesalamine (low certainty).

1 finding from 1 review