Findings

What do systematic reviews say?

1,324 questions · 1,405 findings · 189 reviews

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No studies found 402 · 28.6%GRADE not reported 294 · 20.9%Very low 323 · 23%Low 232 · 16.5%Moderate 117 · 8.3%High 37 · 2.6%

Similar physical activity interventions vs control

IBS symptoms – supervised treadmill exercise · people with IBS

1 finding from 1 review

Physical activity for treatment of irritable bowel syndrome 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 71 participants
Very low

Similar physical activity interventions vs control

IBS symptoms – advice to increase physical activity · people with IBS

1 finding from 1 review

Physical activity for treatment of irritable bowel syndrome 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 93 participants
Very low

Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure

Number of participants with IAD (residual, i.e. not healed) · adults with urinary incontinence

Any skin care procedure (method or frequency of application) probably leads to lower number of participants with IAD (residual, i.e. not healed) (1)… compared with any unstructured skin care procedure (moderate certainty).

1 finding from 1 review

Interventions for preventing and treating incontinence‐associated dermatitis in adults 2016 · Cochrane Headline outcomes only
RR 0.31 [0.12, 0.79]
1 study · 121 participants
Moderate

Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure

Number of participants with IAD (new) · adults with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating incontinence‐associated dermatitis in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure

Number of participants not satisfied with treatment · adults with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating incontinence‐associated dermatitis in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure

Number of participants with pain due to IAD · adults with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating incontinence‐associated dermatitis in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure

Number of participants with pain due to skin care product or procedure · adults with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating incontinence‐associated dermatitis in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure

Adverse reaction due to the skin care product or procedure, e.g. skin irritation, rash, itching, allergic reaction · adults with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating incontinence‐associated dermatitis in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure

Incremental cost‐effectiveness · adults with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating incontinence‐associated dermatitis in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) vs placebo or control

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) probably leads to lower pain intensity (VAS 0-100 mm) compared with control (placebo or no treatment) (moderate certainty).

3 findings from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
2 hours
MD -11.66 [-16.15, -7.17]
10 studies · 685 participants
Moderate
Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
24 hours
MD -21.19 [-28.31, -14.06]
12 studies · 1012 participants
Moderate
Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
6 hours
MD -24.27 [-31.44, -17.11]
9 studies · 535 participants
Moderate

Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) vs placebo or control

Quality of life or participant satisfaction · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
Reported narratively by 2 studies (Wang 2012: SF-36 and SAS - significant reduction in SF-36 bodily pain at 30 days vs baseline, no significant between-group differences; Minor 2009: STAI and PANAS - no significant…
2 studies
GRADE not reported

Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) vs placebo or control

Rescue analgesia · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
Use of rescue analgesia recorded in 7 studies; only 2 reported counts (Tuncer 2014: 2 participants; Bruno 2011: 6 participants); no class/dose/timing reported; not pooled. SoF cell: 'Not reported'.
7 studies
GRADE not reported

Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) vs placebo or control

Time off school or work · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
No studies in this comparison reported this outcome.
0 studies
No studies found

Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) vs placebo or control

Adverse events · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
No studies in this comparison reported any adverse events. SoF cell: 'Not reported'.
0 studies
No studies found

Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) vs placebo or control

Failure to complete orthodontic treatment due to pain · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
No studies reported this outcome.
0 studies
No studies found

Any method, procedure or policy to reduce contaminated aerosols in dental clinics vs Any other method, no treatment or combination of methods

Reduction in volume of contaminated aerosols in the operative environment · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious diseases 2020 · Cochrane All outcomes
Reduction in volume of contaminated aerosols in the operative environment: Not reported (row present in all Summary of findings tables)
0 studies
No studies found

Any method, procedure or policy to reduce contaminated aerosols in dental clinics vs Any other method, no treatment or combination of methods

Incidence of infection of dental staff or patients · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious diseases 2020 · Cochrane All outcomes
Rate of infection of dental staff or patients: Not reported (row present in all Summary of findings tables)
0 studies
No studies found

Root canal medications and canal filling, splinting, extraction of teeth, or surgical removal of any relevant pathology vs Each other, placebo, or no treatment

Outcome not reported · Patients with single and multiple permanent teeth with evidence of any type of external root resorption irrespective of its aetiology,…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of external root resorption 2015 · Cochrane All outcomes
Any follow-up period
None of the studies fulfilled our inclusion criteria and therefore no data analysis was conducted. (Main results: no RCTs that met the inclusion criteria were identified; one ongoing study, NCT00423956, potentially…
0 studies
No studies found

Consumption of xylitol chewing gum by women (mothers) vs Consumption of CHX/xylitol gum by women, or CHX varnish applied to women's dentition

Child microbiological presence (any mutans streptococci colonisation) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age

Consumption of xylitol chewing gum by women (mothers) led to lower child microbiological presence (any mutans streptococci colonisation) compared with consumption of CHX/xylitol gum by women, or CHX varnish applied to…; GRADE not reported.

1 finding from 1 review

Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood caries 2024 · Cochrane All outcomes
RR 0.60 [0.45, 0.81]
2 studies
GRADE not reported

Package of oral health education/promotion including oral hygiene advice for pregnant women, mothers, infants and young children, plus dietary and feeding practice advice for infants and young children vs usual care

Child plaque (any plaque visible on any teeth) · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…

Package of oral health education/promotion including oral hygiene… led to lower child plaque (any plaque visible on any teeth) compared with standard care; GRADE not reported.

1 finding from 1 review

Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood caries 2024 · Cochrane All outcomes
RR 0.35 [0.26, 0.47]
1 study · 441 participants
GRADE not reported