Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,359 questions · 2,491 findings · 249 reviews

No studies found 696 · 27.9%GRADE not reported 213 · 8.6%Very low 611 · 24.5%Low 595 · 23.9%Moderate 315 · 12.6%High 61 · 2.4%

Ear drops (any active treatment) vs no treatment

Proportion of patients (or ears) with complete clearance of ear wax · adults and children with ear wax requiring removal

Ear drops (any active treatment) may leads to higher proportion of patients (or ears) with complete clearance of ear wax compared with no treatment (low certainty).

1 finding from 1 review

Ear drops (any active treatment) vs ear drops (water or saline)

Proportion of patients (or ears) with complete clearance of ear wax · adults and children with ear wax requiring removal

Ear drops (any active treatment) may leads to higher proportion of patients (or ears) with complete clearance of ear wax compared with ear drops (water or saline) (low certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

Postoperative complications ‐ Stroke · children and adults undergoing surgery

Active cerebral oxygenation monitoring showed no clear difference in postoperative stroke ( compared with blinded cerebral oxygenation monitoring (low certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

POD: postoperative delirium ( · children and adults undergoing surgery

Active cerebral oxygenation monitoring showed no clear difference in POD: postoperative delirium ( compared with blinded cerebral oxygenation monitoring (low certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

POCD defined by original studies ‐ mild ( · children and adults undergoing surgery

Active cerebral oxygenation monitoring may leads to lower POCD defined by original studies ‐ mild ( compared with blinded cerebral oxygenation monitoring (low certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

POCD: decline in cognitive function ( · children and adults undergoing surgery

Active cerebral oxygenation monitoring showed no clear difference in POCD: decline in cognitive function ( compared with blinded cerebral oxygenation monitoring (moderate certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

Intraoperative mortality or postoperative mortality: Death ( · children and adults undergoing surgery

Active cerebral oxygenation monitoring showed no clear difference in intraoperative mortality or postoperative mortality: Death ( compared with blinded cerebral oxygenation monitoring (low certainty).

1 finding from 1 review

Active stimulation + other intervention vs other intervention alone

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic pain
3 findings from 1 review

Active stimulation + other intervention vs other intervention alone

Participant‐reported pain relief of 50% or greater · adults with chronic pain

It is very uncertain whether active stimulation + other intervention changes pain intensity. Proportion with ≥ 50% pain relief. compared with other intervention alone (very low certainty).

1 finding from 1 review

Active stimulation + other intervention vs other intervention alone

Adverse event: lead failure/ displacement · adults with chronic pain

The review found no eligible studies for this question.

3 findings from 1 review