Intervention not reported
Diabetic ulcers healed at 1 year. · patients with chronic wounds
The intervention showed no clear difference in diabetic ulcers healed at 1 year. (moderate certainty).
1 finding from 1 review
Intervention not reported
Diabetic ulcers ‐ major amputations · patients with chronic wounds
The intervention showed no clear difference in diabetic ulcers ‐ major amputations (moderate certainty).
1 finding from 1 review
Intervention not reported
Death at any time · patients with acute coronary syndrome
The intervention may leads to lower death at any time (low certainty).
1 finding from 1 review
Intervention not reported
hour Plasma Creatine Phosphokinase · patients with acute coronary syndrome
1 finding from 1 review
Intervention not reported
hour Plasma Creatine Phosphate · patients with acute coronary syndrome
1 finding from 1 review
Intervention not reported
Maximum Plasma Creatine Phosphate · patients with acute coronary syndrome
1 finding from 1 review
Intervention not reported
Single trial only · patients with acute coronary syndrome
1 finding from 1 review
no estimate extracted
1 participants
GRADE not reported
Intervention not reported
Chance of obtaining substantial headache relief (Relief). · Acute migraine
The intervention may leads to higher chance of obtaining substantial headache relief (Relief). (low certainty).
1 finding from 1 review
Birthweight (g) · Pregnant women recruited before 20 weeks' gestation
Caffeinated (experimental group) showed no clear difference in birthweight (g) compared with decaffeinated group (control group) (low certainty).
1 finding from 1 review
Preterm birth · Pregnant women recruited before 20 weeks' gestation
Caffeinated (experimental group) showed no clear difference in preterm birth compared with decaffeinated group (control group) (low certainty).
1 finding from 1 review
Low birthweight · Pregnant women recruited before 20 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Perinatal mortality · Pregnant women recruited before 20 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Sudden infant death syndrome · Pregnant women recruited before 20 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Gestational diabetes · Pregnant women recruited before 20 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neural tube defects (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate leads to lower neural tube defects (All) compared with no intervention, placebo or other micronutrients without folate… (high certainty).
1 finding from 1 review
Miscarriage · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in miscarriage (All) compared with no intervention, placebo or other micronutrients without folate… (moderate certainty).
1 finding from 1 review
Cleft lip (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in cleft lip (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Cleft palate (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in cleft palate (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Congenital cardiovascular anomalies (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in congenital cardiovascular anomalies (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Other congenital anomalies (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in other congenital anomalies (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review