Adverse events · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in adverse events compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Catheter‐related blood stream infection · any patient requiring a PIVC expected to remain in‐situ for at least 3 days
Effects of clinically‐indicated replacement showed no clear difference in catheter‐related blood stream infection (during hospitalisation) compared with routine change of peripheral intravenous catheters (low certainty).
1 finding from 1 review
Thrombophlebitis (during hospitalisation) · any patient requiring a PIVC expected to remain in‐situ for at least 3 days
Effects of clinically‐indicated replacement showed no clear difference in thrombophlebitis (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).
1 finding from 1 review
All‐cause blood stream infection (during hospitalisation) · any patient requiring a PIVC expected to remain in‐situ for at least 3 days
Effects of clinically‐indicated replacement showed no clear difference in all‐cause blood stream infection (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).
1 finding from 1 review
Cost of hospitalisation · any patient requiring a PIVC expected to remain in‐situ for at least 3 days
1 finding from 1 review
Infiltration (during hospitalisation) · any patient requiring a PIVC expected to remain in‐situ for at least 3 days
Effects of clinically‐indicated replacement probably leads to higher infiltration (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).
1 finding from 1 review
Catheter blockage (during hospitalisation) · any patient requiring a PIVC expected to remain in‐situ for at least 3 days
Effects of clinically‐indicated replacement probably leads to higher catheter blockage (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).
1 finding from 1 review
Mortality ( · children aged from 29 days to 12 years with pneumonia
Chest physiotherapy may leads to lower mortality ( compared with no chest physiotherapy (low certainty).
1 finding from 1 review
Clinical resolution · children aged from 29 days to 12 years with pneumonia
Chest physiotherapy showed no clear difference in time to clinical resolution (all parameters) ( compared with no chest physiotherapy (low certainty).
1 finding from 1 review
Adverse events (number of events) ( · children aged from 29 days to 12 years with pneumonia
Chest physiotherapy showed no clear difference in adverse events (number of events) ( compared with no chest physiotherapy (low certainty).
1 finding from 1 review
Plaque · Children and adults with mixed levels of ID; setting home, residential, day care, school, mixed or not specified
It is very uncertain whether special manual toothbrush (self, carer or carer-assisted brushing) changes plaque (short term) compared with conventional manual toothbrush (self, carer or carer-assisted… (very low certainty).
2 findings from 1 review
Gingivitis · Children and adults with mixed levels of ID; setting home, residential, day care, school, mixed or not specified
Special manual toothbrush (self, carer or carer-assisted brushing) showed no clear difference in gingival inflammation (short term) compared with conventional manual toothbrush (self, carer or carer-assisted… (low certainty).
1 finding from 1 review
Gingival inflammation (medium term) · Children and adults with mixed levels of ID; setting home, residential, day care, school, mixed or not specified
It is very uncertain whether special manual toothbrush (self, carer or carer-assisted brushing) changes gingival inflammation (medium term) compared with conventional manual toothbrush (self, carer or carer-assisted… (very low certainty).
1 finding from 1 review
Quality of life changes or long-term, patient-centred outcomes (e.g. tooth retention) · People with intellectual disabilities (ID), living at home, in day care, in hospital or in a residential care setting; all levels of ID as…
The review found no eligible studies for this question.
1 finding from 1 review
Plaque · People with ID (level of ID and age unclear); setting day centre
It is very uncertain whether discussion of individual clinical photographs (plaque highlighted by… changes plaque (medium term) compared with no discussion of clinical photographs, but received the same oral… (very low certainty).
1 finding from 1 review
Calculus · Children and adults with mixed levels of ID; setting home, residential, day care, school, mixed or not specified
Electric toothbrush (self, carer or carer-assisted brushing) showed no clear difference in calculus (medium term) compared with manual toothbrush (self, carer or carer-assisted brushing) (low certainty).
1 finding from 1 review
Postoperative complications after perioperative intervention (e.g. wound‐related complications, secondary surgery, cardiopulmonary complications, admission to intensive care) defined by need for treatment · adult surgical patients consuming 3 or more units of alcohol per day
Perioperative alcohol cessation intervention probably leads to lower postoperative complications after perioperative intervention (e.g.… compared with treatment (moderate certainty).
1 finding from 1 review
Successful quitters (number of abstainers) at the end of the programme (with or without validation by interview, breath test, or alcohol markers) · adult surgical patients consuming 3 or more units of alcohol per day
Perioperative alcohol cessation intervention probably leads to higher successful quitters (number of abstainers) at the end of the… compared with treatment (moderate certainty).
1 finding from 1 review
Post‐treatment scores · patients with functional dyspepsia
1 finding from 1 review
Mean difference symptoms scores · patients with functional dyspepsia
1 finding from 1 review