Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Intervention not reported

Variceal band ligation(17 RCTs, 1640 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes variceal band ligation(17 RCTs, 1640 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers + variceal band ligation(2 RCTs, 313 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes beta‐blockers + variceal band ligation(2 RCTs, 313 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers + nitrates(2 RCTs, 203 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes beta‐blockers + nitrates(2 RCTs, 203 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers plus Nitrates plus Variceal band ligation(No direct RCT) · people with liver cirrhosis and previous oesophageal variceal bleeding

The intervention showed no clear difference in beta‐blockers plus Nitrates plus Variceal band ligation(No direct RCT) (low certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers plus Variceal band ligation(No direct RCT) · people with liver cirrhosis and previous oesophageal variceal bleeding

The intervention showed no clear difference in beta‐blockers plus Variceal band ligation(No direct RCT) (low certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers plus Sclerotherapy(No direct RCT) · people with liver cirrhosis and previous oesophageal variceal bleeding

It is very uncertain whether the intervention changes beta‐blockers plus Sclerotherapy(No direct RCT) (very low certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers plus Sclerotherapy(2 RCTs; 71 participants) · people with liver cirrhosis and previous oesophageal variceal bleeding

The intervention showed no clear difference in beta‐blockers plus Sclerotherapy(2 RCTs; 71 participants) (low certainty).

1 finding from 1 review