Findings

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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Psychological interventions (positive and negative reinforcement) vs no treatment

Sucking cessation (long term) · Children with a non-nutritive sucking habit (digit or pacifier)

Psychological interventions (positive and negative reinforcement) led to higher sucking cessation (long term) compared with no treatment; GRADE not reported.

1 finding from 1 review

EGFR monoclonal antibody (cetuximab or nimotuzumab) plus standard therapy (radiotherapy or chemoradiotherapy) vs Standard therapy alone (radiotherapy or chemoradiotherapy)

Quality of life · People with squamous cell carcinoma of the oral cavity or oropharynx
1 finding from 1 review

Psychological intervention (positive reinforcement) vs Alternative psychological intervention (negative reinforcement)

Sucking cessation (long term) · Children with a non-nutritive sucking habit (digit or pacifier)
1 finding from 1 review

Preformed metal crown (stainless steel), conventional technique vs Aesthetic crown (stainless steel with composite/white veneer), conventional technique

Adverse events: bone resorption · Children with decayed primary molar teeth
1 finding from 1 review
  • Preformed crowns for decayed primary molar teeth 2015 · Cochrane All outcomes
    Six months and four years
    Bone resorption: one case at six months in a tooth treated with a veneer crown; no bone resorption at either the veneer crown or stainless steel sites at four-year follow-up (Analysis 3.2).
    1 study · 11 participants
    Very low

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs no intervention or control intervention (control)

Duration of interruptions to cancer treatment · All patients with cancer who are receiving treatment

It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes duration of interruptions to cancer treatment compared with control (no treatment or standard/usual oral care, e.g. saline rinse) (very low certainty).

1 finding from 1 review

Fixed prostheses cemented to prepared teeth after extraction or decoronation of the ankylosed teeth vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review

Orthodontic appliances (palatal crib) vs no treatment

Correction of posterior crossbite · Children with a non-nutritive sucking habit (digit or pacifier)

The review found no eligible studies for this question.

1 finding from 1 review

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

Adverse effects · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)

The review found no eligible studies for this question.

1 finding from 1 review

Implant-supported crowns after extraction or decoronation of the ankylosed teeth vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review

Preformed metal crown (stainless steel), conventional technique vs Aesthetic crown (stainless steel with composite/white veneer), conventional technique

Adverse events: gingival bleeding · Children with decayed primary molar teeth
1 finding from 1 review
  • Preformed crowns for decayed primary molar teeth 2015 · Cochrane All outcomes
    Six months and four years
    At six months, none (0/11) of the PMC sites had gingival bleeding, but all (11/11) veneer sites had bleeding, 10 of which bled on probing; statistically significant (McNemar's test, P < 0.001). At four years, one case…
    1 study · 11 participants
    Very low

Initiation of water fluoridation (artificial or natural) vs Low/non-fluoridated water (0.4 ppm fluoride or less)

Caries in deciduous teeth (change in dmft) · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years

Initiation of water fluoridation (artificial or natural) may leads to lower caries in deciduous teeth (change in dmft) compared with low/non-fluoridated water (0.4 ppm fluoride or less) (low certainty).

1 finding from 1 review

Xylitol chewing gum vs No treatment or non-cariogenic control

Outcome not reported · Children and adults

The review found no eligible studies for this question.

1 finding from 1 review

Orthodontic appliances (palatal crib) vs no treatment

Occlusion (change in overbite, short term) · Children with a non-nutritive sucking habit (digit or pacifier)

It is very uncertain whether orthodontic appliances (palatal crib) changes occlusion (change in overbite, short term) compared with no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine chewing gum vs Placebo or no intervention (including routine care)

Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

The review found no eligible studies for this question.

1 finding from 1 review

Initiation of water fluoridation (artificial or natural) vs Low/non-fluoridated water (0.4 ppm fluoride or less)

Caries increment in permanent teeth · Children aged about 12 to 16 years (Hardwick 1982), community setting

Initiation of water fluoridation (artificial or natural) led to lower caries in permanent teeth (change in DMFS) compared with low/non-fluoridated water (0.4 ppm fluoride or less); GRADE not reported.

1 finding from 1 review

Chlorhexidine varnish (10%) vs placebo or no treatment

Elevated mutans streptococci levels (>=4 with caries screen; high vs low) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

It is very uncertain whether chlorhexidine varnish (10%) changes elevated mutans streptococci levels (>=4 with caries screen; high vs… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Micro-invasive treatment (proximal sealing or resin infiltration): resin sealant, glass ionomer sealant, polyurethane/adhesive patch, or resin infiltration vs Non-invasive / control treatment

Material deficiency (retention/adaptation loss; re-treatment) · Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in primary or permanent…
1 finding from 1 review

Pilocarpine vs Artificial saliva

Adverse effects (side effects; treatment withdrawals) · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Improvement in occlusion (Peer Assessment Rating (PAR) or other validated scale) · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

The review found no eligible studies for this question.

1 finding from 1 review