Bupropion vs placebo or no pharmacological treatment
Bupropion leads to higher smoking cessation (at least six months of compared with placebo/no pharmacological treatment (high certainty).
- RR 1.6 [1.49, 1.72]50 studies · 18577 participantsHigh
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Bupropion leads to higher smoking cessation (at least six months of compared with placebo/no pharmacological treatment (high certainty).
Bupropion showed no clear difference in serious adverse events compared with placebo/no pharmacological treatment (moderate certainty).
Bupropion leads to higher dropouts due to treatment compared with placebo/no pharmacological treatment (high certainty).
Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in smoking cessation (at least six months of compared with NRT alone (low certainty).
Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in serious adverse events compared with NRT alone (low certainty).
Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in dropouts due to treatment compared with NRT alone (low certainty).
Bupropion plus varenicline showed no clear difference in smoking cessation (at least six months of compared with varenicline alone (moderate certainty).
Bupropion plus varenicline showed no clear difference in serious adverse events compared with varenicline alone (low certainty).
Bupropion plus varenicline showed no clear difference in dropouts due to treatment compared with varenicline alone (low certainty).
It is very uncertain whether the intervention changes serious adverse eventsClinical manifestation and laboratory… (very low certainty).
The intervention showed no clear difference in non‐serious adverse eventsClinical manifestation and laboratory… (low certainty).
Medical/surgical masks showed no clear difference in viral respiratory illness ‐ influenza/COVID‐like illness compared with no masks (moderate certainty).
Hand hygiene showed no clear difference in laboratory‐confirmed influenza compared with control (low certainty).
Hand hygiene may leads to lower composite of acute respiratory illness, influenza‐like illness,… compared with control (low certainty).
Medical/surgical masks showed no clear difference in viral respiratory illness ‐ laboratory‐confirmed influenza/SARS‐CoV‐2 compared with no masks (moderate certainty).
It is very uncertain whether N95 respirators changes viral respiratory illness ‐ clinical respiratory illness compared with medical/surgical masks (very low certainty).
N95 respirators showed no clear difference in viral respiratory illness ‐ influenza‐like illness compared with medical/surgical masks (low certainty).
N95 respirators showed no clear difference in viral respiratory illness ‐ laboratory‐confirmed influenza compared with medical/surgical masks (moderate certainty).