Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Intervention not reported

Deep surgical site infection at 30 days or 90 days, or time points reported by study authors · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events: superficial infection · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures

It is very uncertain whether the intervention changes adverse events: superficial infection (very low certainty).

1 finding from 1 review

Small‐volume residual disease (SVRD) (< 1 cm) vs NMRD

Overall survival: Median length of · women with advanced EOC after PDS

Small‐volume residual disease (SVRD) < 1 cm probably leads to higher overall survival: Median length of compared with NMRD (moderate certainty).

1 finding from 1 review

Large‐volume residual disease (LVRD) > 1 cm vs small‐volume residual disease (SVRD) < 1 cm

Overall survival: Median length of · women with advanced EOC after primary IDS

It is very uncertain whether large‐volume residual disease (LVRD) > 1 cm changes overall survival: Median length of compared with small‐volume residual disease (SVRD) < 1 cm (very low certainty).

1 finding from 1 review

Large‐volume residual disease (LVRD) > 1 cm vs small‐volume residual disease (SVRD) < 1 cm

Progression‐free survival · women with advanced EOC after primary IDS

It is very uncertain whether large‐volume residual disease (LVRD) > 1 cm changes progression‐free survival: Median length of compared with small‐volume residual disease (SVRD) < 1 cm (very low certainty).

1 finding from 1 review

Small‐volume residual disease (SVRD) (< 1 cm) vs NMRD

Progression‐free survival · women with advanced EOC after PDS

Small‐volume residual disease (SVRD) < 1 cm probably leads to higher progression‐free survival: Median length of compared with NMRD (moderate certainty).

1 finding from 1 review