Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
1 study (203 children) reported that black or brown staining on treated lesions was commonly found in both groups, with little or no difference according to whether SDF treatment was given in 3 applications at…
3 studies · 1121 participants
Very low
Smoking cessation · people who smoke
Bupropion leads to higher smoking cessation (at least six months of compared with placebo/no pharmacological treatment (high certainty).
1 finding from 1 review
Serious adverse events · people who smoke
Bupropion showed no clear difference in serious adverse events compared with placebo/no pharmacological treatment (moderate certainty).
1 finding from 1 review
Dropouts due to treatment · people who smoke
Bupropion leads to higher dropouts due to treatment compared with placebo/no pharmacological treatment (high certainty).
1 finding from 1 review
Smoking cessation · people who smoke
Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in smoking cessation (at least six months of compared with NRT alone (low certainty).
1 finding from 1 review
Serious adverse events · people who smoke
Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in serious adverse events compared with NRT alone (low certainty).
1 finding from 1 review
Dropouts due to treatment · people who smoke
Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in dropouts due to treatment compared with NRT alone (low certainty).
1 finding from 1 review
Smoking cessation · people who smoke
Bupropion plus varenicline showed no clear difference in smoking cessation (at least six months of compared with varenicline alone (moderate certainty).
1 finding from 1 review
Serious adverse events · people who smoke
Bupropion plus varenicline showed no clear difference in serious adverse events compared with varenicline alone (low certainty).
1 finding from 1 review
Dropouts due to treatment · people who smoke
Bupropion plus varenicline showed no clear difference in dropouts due to treatment compared with varenicline alone (low certainty).
1 finding from 1 review
Intervention not reported
Serious adverse eventsClinical manifestation and laboratory examination · people with acute herpes zoster (within 7 days of onset of rash)
It is very uncertain whether the intervention changes serious adverse eventsClinical manifestation and laboratory… (very low certainty).
1 finding from 1 review
Intervention not reported
Non‐serious adverse eventsClinical manifestation and laboratory examination · people with acute herpes zoster (within 7 days of onset of rash)
The intervention showed no clear difference in non‐serious adverse eventsClinical manifestation and laboratory… (low certainty).
1 finding from 1 review
Viral respiratory illness ‐ influenza/COVID‐like illness · general population
Medical/surgical masks showed no clear difference in viral respiratory illness ‐ influenza/COVID‐like illness compared with no masks (moderate certainty).
1 finding from 1 review
Influenza assessed by laboratory confirmation · general population and healthcare workers
Hand hygiene showed no clear difference in laboratory‐confirmed influenza compared with control (low certainty).
1 finding from 1 review
Composite of acute respiratory illness, influenza‐like illness, laboratory‐confirmed influenza · general population and healthcare workers
Hand hygiene may leads to lower composite of acute respiratory illness, influenza‐like illness,… compared with control (low certainty).
1 finding from 1 review
Adverse events · general population and healthcare workers
1 finding from 1 review
Viral respiratory illness ‐ laboratory‐confirmed influenza/SARS‐CoV‐2 · general population
Medical/surgical masks showed no clear difference in viral respiratory illness ‐ laboratory‐confirmed influenza/SARS‐CoV‐2 compared with no masks (moderate certainty).
1 finding from 1 review
Adverse events · general population
1 finding from 1 review
Viral illness ‐ clinical respiratory illness · general population and healthcare workers
It is very uncertain whether N95 respirators changes viral respiratory illness ‐ clinical respiratory illness compared with medical/surgical masks (very low certainty).
1 finding from 1 review
Viral respiratory illness ‐ influenza‐like illness · general population and healthcare workers
N95 respirators showed no clear difference in viral respiratory illness ‐ influenza‐like illness compared with medical/surgical masks (low certainty).
1 finding from 1 review