Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,320 questions · 4,561 findings · 388 reviews

No studies found 1,138 · 25%GRADE not reported 886 · 19.4%Very low 1,014 · 22.2%Low 849 · 18.6%Moderate 543 · 11.9%High 131 · 2.9%

Perioperative infraorbital nerve block vs Infiltration of the incision (peri-incisional infiltration)

Analgesia durationTime duration from the end of surgery to the time of first analgesic consumption. Scale from: 0 to 100. · Children up to 13 years of age, undergoing cleft lip repair surgery

Perioperative infraorbital nerve block led to higher time to first analgesic requirement compared with infiltration of the incision (peri-incisional infiltration); GRADE not reported.

1 finding from 1 review

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)

Adverse effects · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative infraorbital nerve block vs Placebo (sham/placebo device)

Need for analgesic prescription for pain (supplemental analgesic requirements) · Children up to 13 years of age, undergoing cleft lip repair surgery

Perioperative infraorbital nerve block may leads to lower need for analgesic prescription for pain (supplemental analgesic… compared with placebo (sham block) (low certainty).

1 finding from 1 review

Motivational interview plus oral health education vs Oral health education

Service use: Emergency medical/dental treatment · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

The review found no eligible studies for this question.

1 finding from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Participant preference · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)
1 finding from 1 review
  • Three studies (Evans 2000; Liu 2006; Zhang 2013) reported participants' preference for future treatment. Zhang 2013: 37/53 children (72%) preferred laser, 10 (22%) drill. Liu 2006: 36/40 (90%) preferred laser, 4 (5%)…
    3 studies
    GRADE not reported

Intervention not reported

Unintended pregnancy · Male and female adolescents aged 10 years to 19 years

The intervention showed no clear difference in unintended pregnancy (moderate certainty).

1 finding from 1 review

Intervention not reported

Use of birth control methods (consistent condom use) · Male and female adolescents aged 10 years to 19 years

The intervention showed no clear difference in use of birth control methods (consistent condom use) (low certainty).

1 finding from 1 review

Intervention not reported

Use of birth control methods (hormonal contraceptives) · Male and female adolescents aged 10 years to 19 years

It is very uncertain whether the intervention changes use of birth control methods (hormonal contraceptives) (very low certainty).

1 finding from 1 review

Intervention not reported

Sexually Transmitted Diseases · Male and female adolescents aged 10 years to 19 years

The intervention showed no clear difference in sexually Transmitted Diseases (low certainty).

1 finding from 1 review

Intervention not reported

Unintended pregnancy · Male and female adolescents aged 10 years to 9 years

The intervention probably leads to lower unintended pregnancy (moderate certainty).

1 finding from 1 review

Intervention not reported

Initiation of sexual intercourse (mixed gender) · Male and female adolescents aged 10 years to 9 years

The intervention showed no clear difference in initiation of sexual intercourse (mixed gender) (moderate certainty).

1 finding from 1 review

Intervention not reported

Use of birth control methods (condom use in last sex) · Male and female adolescents aged 10 years to 9 years

The intervention showed no clear difference in use of birth control methods (condom use in last sex) (moderate certainty).

1 finding from 1 review

Intervention not reported

Use of birth control methods (consistent condom use) · Male and female adolescents aged 10 years to 9 years

The intervention showed no clear difference in use of birth control methods (consistent condom use) (low certainty).

1 finding from 1 review

Intervention not reported

Sexually Transmitted Diseases · Male and female adolescents aged 10 years to 9 years

It is very uncertain whether the intervention changes sexually Transmitted Diseases (very low certainty).

1 finding from 1 review

Intervention not reported

Use of birth control methods (condom use in last sex) · Male and female adolescents aged 10 years to 19 years

The intervention showed no clear difference in use of birth control methods (condom use in last sex) (high certainty).

1 finding from 1 review

Intervention not reported

Use of birth control methods (hormonal contraceptives) · Male and female adolescents aged 10 years to 19 years

The intervention leads to higher use of birth control methods (hormonal contraceptives) (high certainty).

1 finding from 1 review

Intervention not reported

Sexually Transmitted Diseases · Male and female adolescents aged 10 years to 19 years

The intervention showed no clear difference in sexually Transmitted Diseases (high certainty).

1 finding from 1 review

Intervention not reported

Use of birth control methods (condom use at last sex) · Male and female adolescents aged 10 years to 19 years

The intervention probably leads to higher use of birth control methods (condom use at last sex) (moderate certainty).

1 finding from 1 review

Intervention not reported

Initiation of sexual intercourse (mixed gender) · Male and female adolescents aged 10 years to 19 years

The intervention showed no clear difference in initiation of sexual intercourse (mixed gender) (low certainty).

1 finding from 1 review

Intervention not reported

Unintended pregnancy · Male and female adolescents aged 10 years to 19 years

The intervention showed no clear difference in unintended pregnancy (low certainty).

1 finding from 1 review