Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,749 questions · 14,261 findings · 832 reviews

No studies found 3,655 · 25.6%GRADE not reported 2,111 · 14.8%Very low 3,646 · 25.6%Low 3,028 · 21.2%Moderate 1,501 · 10.5%High 320 · 2.2%

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Ultrasound‐guided foam sclerotherapy vs SFJ ligation and stripping (HL/S)

Technical success · people with GSV incompetence

Ultrasound‐guided foam sclerotherapy (UGFS) may leads to lower technical success (< 5 years) compared with SFJ ligation and stripping (HL/S) (low certainty).

2 findings from 1 review

Endovenous laser ablation (EVLA) vs foam sclerotherapy

Technical success · people with GSV incompetence

Endovenous laser ablation (EVLA) showed no clear difference in technical success (< 5 years) compared with ultrasound‐guided foam sclerotherapy (UGFS) (low certainty).

2 findings from 1 review

Fluoexetine vs placebo

Change in weight (kg) · People who have quit smoking

Fluoexetine showed no clear difference in mean weight change (kg) at end of treatment compared with placebo (low certainty).

2 findings from 1 review