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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

3,601 questions in 252 reviews · Pregnancy and Childbirth

current versions
No studies 726 · 20.2%Ungraded 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
NSAID vs herbal analgesia
Any breastfeeding at 6 weeks postpartum · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
TENS vs no TENS
Adequate pain relief as reported by the woman (during next breast feed) · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
RR 4 [0.5, 31.98]1 study · 32 participantsVery low
TENS vs no TENS
Need for additional pain relief · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
TENS vs no TENS
Maternal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extracted32 participantsUngraded
TENS vs no TENS
Neonatal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
TENS vs no TENS
Duration of hospital stay · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
TENS vs no TENS
Any breastfeeding at hospital discharge · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
TENS vs no TENS
Any breastfeeding at 6 weeks postpartum · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
NSAID vs placebo
Duration of hospital stay · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
NSAID vs placebo
Any breastfeeding at hospital discharge · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
NSAID vs placebo
Any breastfeeding at 6 weeks postpartum · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
NSAID vs opioid
Adequate pain relief as reported by the woman (5 to 8 hours) · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
RR 1.33 [1.13, 1.57]5 studies · 560 participantsModerate
NSAID vs opioid
Need for additional pain relief (6 to 8 hours) · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
RR 0.37 [0.12, 1.12]2 studies · 232 participantsLow
Labour induction vs expectant management (infant/child outcomes)
Perinatal death (intrauterine deaths plus neonatal deaths in the first week of life) · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 0.31 [0.15, 0.64]22 studies · 18795 participantsHigh
Labour induction vs expectant management (maternal outcomes)
Perineal trauma (severe perineal tear) · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 1.04 [0.85, 1.26]5 studies · 11589 participantsLow
Labour induction vs expectant management (maternal outcomes)
Postpartum haemorrhage · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 1.02 [0.91, 1.15]9 studies · 12609 participantsModerate
Labour induction vs expectant management (maternal outcomes)
Breastfeeding at discharge · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 1 [0.96, 1.04]2 studies · 7487 participantsModerate
Labour induction vs expectant management (maternal outcomes)
Postnatal depression · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Labour induction vs expectant management (maternal outcomes)
Length of maternal hospital stay (days) · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
MD 0.197 studies · 4120 participantsVery low
Labour induction vs expectant management (infant/child outcomes)
Stillbirth · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 0.3 [0.12, 0.75]22 studies · 18795 participantsHigh
Labour induction vs expectant management (infant/child outcomes)
Admission to neonatal intensive care unit · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 0.88 [0.8, 0.96]17 studies · 17826 participantsHigh
Labour induction vs expectant management (infant/child outcomes)
Neonatal encephalopathy · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 0.69 [0.37, 1.31]2 studies · 8851 participantsLow
Labour induction vs expectant management (infant/child outcomes)
Apgar score less than 7 at 5 minutes · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 0.73 [0.56, 0.96]20 studies · 18345 participantsModerate
Labour induction vs expectant management (infant/child outcomes)
Neonatal (birth) trauma · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 0.97 [0.63, 1.49]5 studies · 13106 participantsModerate
Labour induction vs expectant management (infant/child outcomes)
Neurodevelopment at childhood · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Labour induction vs expectant management (maternal outcomes)
Caesarean section · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 0.9 [0.85, 0.95]31 studies · 21030 participantsModerate
Labour induction vs expectant management (maternal outcomes)
Operative vaginal birth (forceps or ventouse) · pregnant women at or beyond 37 weeks gestation
Induction of labour at or beyond 37 weeks' gestation (2020) · Cochrane
RR 1.03 [0.96, 1.1]22 studies · 18584 participantsModerate
Cooling treatment (ice pack or cold gel pad) vs no treatment
Perineal pain within 4 ‐ 6 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 100 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Adverse effects on perineal wound healing: Day 5 ‐ Wound not healing · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 1.24 [0.34, 4.58]1 study · 315 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Adverse effects on perineal wound healing: Day 5 ‐ Wound edges gaping · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 2.56 [0.58, 11.33]1 study · 315 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Maternal views and experiences of treatment ‐ Satisfaction with overall perineal care (good + very good + excellent) Day 10 · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 1.07 [0.97, 1.18]1 study · 308 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Maternal views and experiences of treatment ‐ Psychospiritual comfort within 6 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 100 participantsLow
Cooling treatment (ice pack or cold gel pad) vs no treatment
Maternal views and experiences of treatment ‐ Sociocultural comfort · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 100 participantsLow
Cooling treatment (cold gel pad)+compression vs placebo (gel pad+compression)
Perineal pain within 4 ‐ 6 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 250 participantsLow
Cooling treatment (cold gel pad)+compression vs placebo (gel pad+compression)
Perineal pain within 24 ‐ 48 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 250 participantsLow
Cooling treatment (cold gel pad)+compression vs placebo (gel pad+compression)
Perineal oedema 24 ‐ 48 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 250 participantsLow
Cooling treatment (cold gel pad)+compression vs placebo (gel pad+compression)
Perineal bruising 24 ‐ 48 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 250 participantsUngraded
Cooling treatment (cold gel pad)+compression vs placebo (gel pad+compression)
Adverse effects · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Cooling treatment (ice pack or cold gel pad) vs no treatment
Perineal pain within 24 hours of giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 1.03 [0.82, 1.29]1 study · 316 participantsVery low
Cooling treatment (cold gel pad)+compression vs placebo (gel pad+compression)
Satisfaction with perineal care · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 250 participantsLow
Cooling treatment (ice pack) vs placebo (water pack)
Perineal pain within 24 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 63 participantsUngraded
Cooling treatment (ice pack) vs placebo (water pack)
Perineal oedema within 4 ‐ 6 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.96 [0.5, 1.86]1 study · 63 participantsLow
Cooling treatment (ice pack) vs placebo (water pack)
Perineal oedema within 24 hours after giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.36 [0.08, 1.59]1 study · 63 participantsLow
Cooling treatment (ice pack) vs placebo (water pack)
Adverse effects on perineal healing · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted1 study · 63 participantsUngraded
Cooling treatment (ice pack) vs placebo (water pack)
Maternal views and experiences with treatment ‐ Satisfied with treatment · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.91 [0.77, 1.08]1 study · 63 participantsVery low
Cooling treatment (ice pack) vs placebo (water pack)
Maternal views and experiences with treatment ‐ Would repeat treatment in future childbirth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.88 [0.75, 1.04]1 study · 63 participantsVery low
Cooling treatment (ice pack) vs placebo (water pack)
Maternal views and experiences with treatment ‐ Would recommend treatment · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.89 [0.77, 1.03]1 study · 63 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal pain within 4 ‐ 6 hours of giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.57 [0.26, 1.24]1 study · 49 participantsVery low
Cooling treatment (ice pack) vs cooling treatment (cold gel pad)
Perineal pain within 24 hours of giving birth ‐ Moderate + severe pain · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
RR 0.98 [0.78, 1.22]2 studies · 264 participantsVery low
Cooling treatment (ice pack or cold gel pad) vs no treatment
Perineal pain within 24 hours of giving birth · Women with perineal trauma (tear or episiotomy, or both) sustained during childbirth
Local cooling for relieving pain from perineal trauma sustained during childbirth (2020) · Cochrane
no estimate extracted3 studies · 166 participantsVery low