Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

331 questions · 353 findings · 56 reviews

No studies found 41 · 11.6%GRADE not reported 74 · 21%Very low 128 · 36.3%Low 66 · 18.7%Moderate 32 · 9.1%High 12 · 3.4%

Intervention not reported

Radiographic progression · people with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Short‐term serious adverse events · people with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Long‐term adverse effects or toxicity · people with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Withdrawals – overall (at 8 to 12 weeks) · people with rheumatoid arthritis

The intervention may leads to lower withdrawals – overall (at 8 to 12 weeks) (low certainty).

1 finding from 1 review

Xylitol syrup (high dose, 8 g/day) vs Control (low-dose xylitol, 2.67 g/day) syrup

Adverse effects (loose stools, diarrhoea) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review

Xylitol lozenges (5 g/day) vs placebo control

Adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, loose stool or diarrhoea) · adults
1 finding from 1 review

Xylitol tablets (200 to 600 mg/day) via slow-release pacifier/dummy vs Control (sorbitol) tablets

Number of infants with a caries increment (dmfs) · Infants (primary teeth)

It is very uncertain whether xylitol tablets (200 to 600 mg/day) via slow-release pacifier/dummy changes number of infants with a caries increment (dmfs) compared with control (sorbitol) tablets (very low certainty).

1 finding from 1 review