Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

416 questions · 426 findings · 56 reviews

No studies found 109 · 25.6%GRADE not reported 23 · 5.4%Very low 109 · 25.6%Low 106 · 24.9%Moderate 64 · 15%High 15 · 3.5%

Summary of findings: pioglitazone monotherapy vs another pharmacological glucose‐lowering monotherapy

Metformin · people at increased risk for developing type 2 diabetes
2 findings from 1 review

Summary of findings: pioglitazone monotherapy vs another pharmacological glucose‐lowering monotherapy

Acarbose · people at increased risk for developing type 2 diabetes
2 findings from 1 review

Summary of findings: pioglitazone monotherapy vs another pharmacological glucose‐lowering monotherapy

Repaglinide · people at increased risk for developing type 2 diabetes
2 findings from 1 review

Summary of findings: pioglitazone monotherapy vs another pharmacological glucose‐lowering monotherapy

Metformin Diagnostic criteria: 2 studies applied the WHO 1999 criteria for 'prediabetes' (FPG > 6.1 mmol/L and < 7.0 mmol/L and/or a 2‐h glucose < 11.1 mmol/L after a 75 g OGTT; Chen 2007a; Zeng 2013) · people at increased risk for developing type 2 diabetes

Summary of findings: pioglitazone monotherapy showed no clear difference in metformin Diagnostic criteria: 2 studies applied the WHO 1999… compared with another pharmacological glucose‐lowering monotherapy (low certainty).

1 finding from 1 review

Summary of findings: pioglitazone monotherapy vs another pharmacological glucose‐lowering monotherapy

Acarbose Diagnostic criteria: 1 study applied the WHO 1999 criteria for prediabetes (FPG > 6.1 mmol/L and < 7.0 mmol/L and/or a 2‐h glucose < 11.1 mmol/L after a 75 g OGTT; Chen 2007a) · people at increased risk for developing type 2 diabetes
1 finding from 1 review

Summary of findings: pioglitazone monotherapy vs another pharmacological glucose‐lowering monotherapy

Repaglinide Diagnostic criteria: 1 study applied the ADA 2010 criteria (FPG ≥ 5.6 mmol/L and < 6.9 mmol/L and 2‐h glucose ≥ 7.8 mmol/L or < 11.0 mmol/L after a 75 g OGTT; Zhang 2007) · people at increased risk for developing type 2 diabetes
1 finding from 1 review

Summary of findings for IV fenoterol bromhydrate vs emergency delivery

Caesarean section · women with a non‐reassuring fetal heart trace during labour but without uterine tachysystole

Summary of findings for IV fenoterol bromhydrate probably leads to higher caesarean delivery compared with emergency delivery (moderate certainty).

1 finding from 1 review

Summary of findings for IV fenoterol bromhydrate vs emergency delivery

Apgar score less than 7 at 5 minutes · women with a non‐reassuring fetal heart trace during labour but without uterine tachysystole

Summary of findings for IV fenoterol bromhydrate showed no clear difference in 5‐minute Apgar score < 7 compared with emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for IV fenoterol bromhydrate vs emergency delivery

Umbilical artery pH < 7.1 · women with a non‐reassuring fetal heart trace during labour but without uterine tachysystole

Summary of findings for IV fenoterol bromhydrate showed no clear difference in umbilical artery pH < 7.1 compared with emergency delivery (low certainty).

1 finding from 1 review