Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

335 questions · 344 findings · 21 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 95 · 27.6%GRADE not reported 22 · 6.4%Very low 48 · 14%Low 100 · 29.1%Moderate 55 · 16%High 24 · 7%

Intervention not reported

Death within 5 years · patients with early‐stage cervical cancer (FIGO stages IB1, IB2 or IIA)

The intervention showed no clear difference in death within 5 years (moderate certainty).

1 finding from 1 review

Intervention not reported

Disease progression within 5 years · patients with early‐stage cervical cancer (FIGO stages IB1, IB2 or IIA)

The intervention probably leads to lower disease progression within 5 years (moderate certainty).

1 finding from 1 review

Intervention not reported

Haematological adverse events (grade 3 or 4) · patients with early‐stage cervical cancer (FIGO stages IB1, IB2 or IIA)

The intervention showed no clear difference in haematological adverse events (grade 3 or 4) (moderate certainty).

1 finding from 1 review

Intervention not reported

Gastrointestinal adverse events (grade 3 or 4) · patients with early‐stage cervical cancer (FIGO stages IB1, IB2 or IIA)

The intervention showed no clear difference in gastrointestinal adverse events (grade 3 or 4) (moderate certainty).

1 finding from 1 review

Intervention not reported

Genitourinary adverse events (grade 3 or 4) · patients with early‐stage cervical cancer (FIGO stages IB1, IB2 or IIA)

The intervention showed no clear difference in genitourinary adverse events (grade 3 or 4) (moderate certainty).

1 finding from 1 review