Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

461 questions · 475 findings · 59 reviews · Headline outcomes only

No studies found 112 · 23.6%GRADE not reported 13 · 2.7%Very low 66 · 13.9%Low 140 · 29.5%Moderate 112 · 23.6%High 32 · 6.7%

Clobazam vs phenytoin

Retention [ · drug‐naïve people with focal or generalized seizures with solitary cysticercus granuloma

Clobazam may leads to higher retention at 6 months (measured by the number of treatment failures… compared with phenytoin (low certainty).

1 finding from 1 review

Hearing aid vs sound generator

Tinnitus symptom severity · adults with tinnitus
3 findings from 1 review

Intervention not reported

Time to treatment withdrawal ‐ all participants Range of · adults and children with newly diagnosed partial onset or generalised onset seizures

The intervention may leads to higher time to treatment withdrawal ‐ all participants Range of (low certainty).

1 finding from 1 review

Intervention not reported

Time to first seizure ‐ all participants Range of · adults and children with newly diagnosed partial onset or generalised onset seizures

The intervention showed no clear difference in time to first seizure ‐ all participants Range of (moderate certainty).

1 finding from 1 review

Intervention not reported

Time to first seizure ‐ stratified by epilepsy type ‐ Partial onset Range of · adults and children with newly diagnosed partial onset or generalised onset seizures

The intervention showed no clear difference in time to first seizure ‐ stratified by epilepsy type ‐ Partial onset… (moderate certainty).

1 finding from 1 review

Intervention not reported

Time to treatment withdrawal ‐ stratified by seizure type ‐ Partial onset Range of · adults and children with newly diagnosed partial onset or generalised onset seizures

The intervention may leads to higher time to treatment withdrawal ‐ stratified by seizure type ‐ Partial… (low certainty).

1 finding from 1 review

Intervention not reported

Time to 12‐month remission ‐ all participants Range of · adults and children with newly diagnosed partial onset or generalised onset seizures

The intervention showed no clear difference in time to 12‐month remission ‐ all participants Range of (moderate certainty).

1 finding from 1 review

Intervention not reported

Time to 12‐month remission ‐ stratified by seizure type ‐ Partial Onset Range of · adults and children with newly diagnosed partial onset or generalised onset seizures

The intervention showed no clear difference in time to 12‐month remission ‐ stratified by seizure type ‐ Partial… (moderate certainty).

1 finding from 1 review

Intervention not reported

Time to 6‐month remission ‐ all participants Range of · adults and children with newly diagnosed partial onset or generalised onset seizures

The intervention showed no clear difference in time to 6‐month remission ‐ all participants Range of (moderate certainty).

1 finding from 1 review

Intervention not reported

Time to 6‐month remission ‐ stratified by seizure type ‐ Partial onset Range of · adults and children with newly diagnosed partial onset or generalised onset seizures

The intervention showed no clear difference in time to 6‐month remission ‐ stratified by seizure type ‐ Partial… (moderate certainty).

1 finding from 1 review