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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

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No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Orthodontic appliances (palatal crib) vs no treatment

Adverse events · Children with a non-nutritive sucking habit (digit or pacifier)
1 finding from 1 review

Initiation of water fluoridation (artificial or natural) vs Low/non-fluoridated water (0.4 ppm fluoride or less)

Dental caries in adults · adults

The review found no eligible studies for this question.

1 finding from 1 review
  • Water fluoridation for the prevention of dental caries 2015 · Cochrane All outcomes
    Adults
    No studies that aimed to determine the effectiveness of water fluoridation for preventing caries in adults met the review's inclusion criteria. There are no data to determine the effect of water fluoridation on caries…
    0 studies
    No studies found

Chlorhexidine oral product (one formulation/concentration) vs Another chlorhexidine formulation, concentration or application frequency

Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

The review found no eligible studies for this question.

1 finding from 1 review

Orthodontic appliances (palatal crib) vs no treatment

Sucking cessation (long term) · Children with a non-nutritive sucking habit (digit or pacifier)

Orthodontic appliances (palatal crib) led to higher sucking cessation (long term) compared with no treatment; GRADE not reported.

1 finding from 1 review

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs no intervention or control intervention (control)

Oral mucositis (severe) · All patients with cancer who are receiving treatment

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… probably leads to lower oral mucositis (severe) compared with control (no treatment or standard/usual oral care, e.g. saline rinse) (moderate certainty).

3 findings from 1 review

Higher drinking-water fluoride exposure vs Lower water fluoride concentration (concurrent control)

Dental fluorosis of aesthetic concern (Dean's Index, TFI, TSIF) · Populations of all ages (mostly children) exposed to drinking water with differing fluoride concentrations

Higher water fluoride concentration (fluoridated water; natural or… may leads to higher dental fluorosis of aesthetic concern (Dean's Index, TFI, TSIF) compared with lower water fluoride concentration (concurrent control) (low certainty).

1 finding from 1 review

Repositioning of ankylosed teeth after osteotomy followed or not by distraction osteogenesis, or after luxation vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs High-dose leucovorin rinse

Oral mucositis (severe) · Patients with osteosarcoma (bone cancer) receiving high-dose methotrexate, vincristine and leucovorin
1 finding from 1 review

Xylitol sucking tablets (1 g/day) vs no treatment

Number of infants with a caries increment · Infants/young children (primary teeth; baseline about 1 to 3 years)

Xylitol sucking tablets (1 g/day) showed no clear difference in number of infants with a caries increment compared with no treatment; GRADE not reported.

1 finding from 1 review

Palatal arch vs Palatal crib (alternative orthodontic appliance)

Sucking cessation (short term) · Children with a non-nutritive sucking habit (digit or pacifier)

It is very uncertain whether palatal arch changes sucking cessation (short term) compared with palatal crib (alternative orthodontic appliance) (very low certainty).

1 finding from 1 review

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs no intervention or control intervention (control)

Number of days of treatment with opioid analgesics · All patients with cancer who are receiving treatment

The review found no eligible studies for this question.

2 findings from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Duration of orthodontic treatment, number of visits during active treatment (scheduled and unscheduled) and duration of visits · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

The review found no eligible studies for this question.

1 finding from 1 review

Non-specific immunotherapy (recombinant interleukin-2 or BCG cell wall preparation) plus standard therapy vs Standard therapy alone (radiotherapy or chemoradiotherapy)

Disease-free survival · People with squamous cell carcinoma of the oral cavity or oropharynx

It is very uncertain whether non-specific immunotherapy (recombinant interleukin-2 or BCG cell… changes disease-free survival compared with standard therapy alone (very low certainty).

1 finding from 1 review