Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,747 questions · 3,943 findings · 594 reviews

No studies found 784 · 19.9%GRADE not reported 530 · 13.4%Very low 1,040 · 26.4%Low 981 · 24.9%Moderate 444 · 11.3%High 164 · 4.2%

Intervention not reported

Incidence of AAD · Children receiving antibiotic treatment between 4 and 28 days duration for a variety of infections

The intervention probably leads to lower incidence of AAD (moderate certainty).

1 finding from 1 review

Intervention not reported

Incidence of AAD: Probiotic dose (≥5 billion CFUs of probiotics/day) · Children receiving antibiotic treatment between 4 and 28 days duration for a variety of infections

The intervention probably leads to lower incidence of AAD: Probiotic dose (≥5 billion CFUs of probiotics/day) (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events · Children receiving antibiotic treatment between 4 and 28 days duration for a variety of infections

The intervention showed no clear difference in adverse events (low certainty).

1 finding from 1 review

Conventional restorative treatment with compomer vs Other network treatments

Treatment success rate · Primary teeth with dentin caries lesions on occlusal surfaces

CRT with compomer ranked first for treatment success in the occlusal-surface network (low certainty).

1 finding from 1 review

Silver diamine fluoride twice annually vs Other network treatments

Caries lesion arrestment · Primary teeth with dentin caries lesions on occlusal and smooth surfaces

Silver diamine fluoride twice annually ranked first for caries lesion arrestment in the occlusal- and smooth-surface network (moderate certainty).

1 finding from 1 review

Hall technique vs Other network treatments

Treatment success rate · Primary teeth with dentin caries lesions on occlusoproximal surfaces

The Hall technique ranked first for treatment success in the occlusoproximal-surface network (low certainty).

1 finding from 1 review

Conventional restorative treatment with resin composite (CRT-RC) vs Sealing

Treatment success (caries lesion arrest or restoration survival) · Children with dentin caries lesions in the outer half of dentin on occlusal surfaces of primary teeth

Conventional restorative treatment with resin composite gave a higher treatment success rate than resin sealing for outer-half occlusal dentin caries in primary teeth (2 studies; low certainty).

1 finding from 1 review

Intervention not reported

Tardive dyskinesia: Not improved to a clinically important extent · patients with antipsychotic‐induced TD

The intervention may leads to lower tardive dyskinesia: Not improved to a clinically important extent (low certainty).

1 finding from 1 review

Intervention not reported

Tardive dyskinesia: Deterioration of symptoms · patients with antipsychotic‐induced TD

It is very uncertain whether the intervention changes tardive dyskinesia: Deterioration of symptoms (very low certainty).

1 finding from 1 review

Intervention not reported

Acceptability of treatment: Leaving the study early · patients with antipsychotic‐induced TD

It is very uncertain whether the intervention changes acceptability of treatment: Leaving the study early (very low certainty).

1 finding from 1 review

Intervention not reported

Social confidence, social inclusion, social networks, or personalised quality of life measures · patients with antipsychotic‐induced TD

The review found no eligible studies for this question.

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

All‐cause mortality at 30 days · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes all‐cause mortality at 30 days compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

All‐cause mortality at 5 years · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes all‐cause mortality at 5 years compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

Reintervention Number of women with reintervention · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes number of participants with reintervention at 5 years compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

Irreversible shunt occlusion at 5 years · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes irreversible shunt occlusion at 5 years compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

Encephalopathy · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes number of participants with encephalopathy at 5 years compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review