Pain at 48 hours (VAS 0-10) · Adults (>18 years) with established dry socket following permanent tooth extraction
Topical anaesthetic gel (prilocaine-lidocaine) showed no clear difference in pain at 48 hours (VAS 0-10) compared with eugenol; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine gel (0.2%, intrasocket) showed no clear difference in presence of dry socket compared with chlorhexidine rinse (0.12%) (low certainty).
1 finding from 1 review
Healing of MRONJ (remission) · People with established (manifest) MRONJ
It is very uncertain whether teriparatide 56.5 microg weekly in addition to standard care changes healing of MRONJ (remission) compared with teriparatide 20 microg daily in addition to standard care (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Tap water irrigation (monoject syringe) led to lower presence of dry socket compared with no rinsing; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine gel 1% showed no clear difference in presence of dry socket compared with chlorhexidine gel 0.2%; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Honey (Manuka, topical) showed no clear difference in presence of dry socket compared with chlorhexidine rinse (0.2%); GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine gel (0.2%, intrasocket) probably leads to lower presence of dry socket compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Quality of life · People with established (manifest) MRONJ
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Artemisia desertorum spreng (Shahaosan) showed no clear difference in presence of dry socket compared with artemisia desertorum spreng (Yunnan); GRADE not reported.
1 finding from 1 review
MRONJ (incidence proportion) · People with cancer treated with intravenous bisphosphonates undergoing dental extractions (at risk of MRONJ)
It is very uncertain whether dental extraction protocol with plasma rich in growth factors (PRGF)… changes MRONJ (incidence proportion) compared with standard dental extraction protocol without PRGF (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Oral tissue patch led to lower presence of dry socket compared with placebo or control; GRADE not reported.
1 finding from 1 review
Time to initial pain relief (minutes) · Adults (>18 years) with established dry socket following permanent tooth extraction
Alvogyl led to lower time to initial pain relief (minutes) compared with zinc oxide eugenol; GRADE not reported.
1 finding from 1 review
MRONJ (incidence rate: cases per patient-year) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ)
It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence rate: cases per patient-year) compared with standard care (very low certainty).
1 finding from 1 review
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
Reported incidence or prevalence of root resorption of the impacted canine and/or incisors and/or first premolars · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
It is very uncertain whether ARP with alloplast plus barrier membrane changes changes in vertical height of alveolar ridge (mm) compared with ARP with alloplast without membrane (very low certainty).
1 finding from 1 review
Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
It is very uncertain whether non-selective carious tissue removal and conventional restoration (CR) changes failure of therapy compared with selective carious tissue removal (selective excavation, SE) (very low certainty).
3 findings from 1 review
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
The review found no eligible studies for this question.
1 finding from 1 review
Outcome not reported
0 studies
No studies found
Incidence of eruption of the PDC into the mouth · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
Double primary (canine and first molar) tooth extraction led to higher incidence of eruption of the PDC into the mouth compared with single primary (canine) tooth extraction; GRADE not reported.
4 findings from 1 review
RR 1.28 [1.06, 1.54]
2 studies · 96 participants
GRADE not reported
RR 0.68 [0.35, 1.31]
3 studies · 119 participants
Very low
RR 0.61 [0.29, 1.25]
1 study · 23 participants
GRADE not reported
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