Intervention not reported
TXA given intravenously at a total dose of 2 g postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin) Comparator…
1 finding from 1 review
no estimate extracted
2 participants
Low
Intervention not reported
TXA given intravenously at a total dose of 2 g intraoperatively and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin) Comparator…
1 finding from 1 review
no estimate extracted
2 participants
Very low
Intervention not reported
Aprotinin given intravenously · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin) Comparator…
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
TXA given intra‐articularly at a total dose of 1 g intraoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin) Comparator…
1 finding from 1 review
no estimate extracted
1 participants
Low
Intervention not reported
TXA given intravenously at a total dose of 1 g intraoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin) Comparator…
1 finding from 1 review
no estimate extracted
1 participants
Low
Intervention not reported
TXA given intravenously and intra‐articularly at a total dose of 2 g intraoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…
1 finding from 1 review
no estimate extracted
2 participants
Moderate
Validated pain scales · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Discomfort/pain · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain (PIPP) · neonates with mechanical ventilation
Familiar odour (breast milk smell) showed no clear difference in PIPP during endotracheal suctioning Range of scale 0 to 21. Lower… compared with standard care (low certainty).
1 finding from 1 review
Physiological indicators · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Heart rate · neonates with mechanical ventilation
Familiar odour (breast milk smell) showed no clear difference in heart rate compared with standard care (low certainty).
1 finding from 1 review
SaO 2 during endotracheal suctioning · neonates with mechanical ventilation
Familiar odour (breast milk smell) showed no clear difference in saO 2 during endotracheal suctioning compared with standard care (low certainty).
1 finding from 1 review
Behavioural indicators · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
— · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Discomfort/pain · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain (PIPP) · neonates with mechanical ventilation
White noise showed no clear difference in PIPP during endotracheal suctioning Range of scale 0 to 21 Lower… compared with standard care (low certainty).
1 finding from 1 review
Physiological indicators · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain (PIPP) · neonates with mechanical ventilation
Facilitated tucking / four‐handed care / gentle human touch showed no clear difference in PIPP during endotracheal suctioning Range of scale 0 to 21. Lower… compared with standard care (moderate certainty).
1 finding from 1 review
Heart rate · neonates with mechanical ventilation
White noise showed no clear difference in heart rate compared with standard care (low certainty).
1 finding from 1 review
SaO 2 · neonates with mechanical ventilation
White noise showed no clear difference in saO 2 compared with standard care (low certainty).
1 finding from 1 review