Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,736 questions · 15,265 findings · 1,163 reviews · Headline outcomes only

No studies found 3,871 · 25.4%GRADE not reported 810 · 5.3%Very low 4,242 · 27.8%Low 3,879 · 25.4%Moderate 1,999 · 13.1%High 464 · 3%

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Early vs delayed mobilisation

Self‐reported shoulder function: Croft Shoulder Disability Score (1 or more problems) · adults with minimally displaced or displaced (2‐part or 3‐part) proximal humeral fractures treated non‐surgically (5 trials)

It is very uncertain whether early changes self‐reported shoulder function: Croft Shoulder Disability Score (1… compared with delayed mobilisation (very low certainty).

2 findings from 1 review

Surgical vs non‐surgical treatment

Functional outcomes · (mainly older) adults with most types of displaced proximal humeral fracturesa (10 trials)

Surgical showed no clear difference in functional scoresf(higher = better outcome) compared with non‐surgical treatment (high certainty).

3 findings from 1 review

Surgical vs non‐surgical treatment

Quality of life: EQ‐5D (0: dead to 1: best quality of life) · (mainly older) adults with most types of displaced proximal humeral fracturesa (10 trials)

Surgical showed no clear difference in quality of life: EQ‐5D (0: dead to 1: best quality of life) compared with non‐surgical treatment (high certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Adverse events / complications ‐ Number of participants with complications · (mainly older) adults with most types of displaced proximal humeral fracturesa (10 trials)

Surgical showed no clear difference in adverse events / complications ‐ Number of participants with… compared with non‐surgical treatment (low certainty).

1 finding from 1 review

Locking plate vs locking intramedullary nail

Self‐reported shoulder function · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)

Locking plate showed no clear difference in self‐reported shoulder function: functional scoresb(higher = better… compared with locking intramedullary nail (low certainty).

3 findings from 1 review

Locking plate vs locking intramedullary nail

Adverse events: number of participants with complications · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)

It is very uncertain whether locking plate changes adverse events: number of participants with complications compared with locking intramedullary nail (very low certainty).

1 finding from 1 review

Reverse total shoulder arthroplasty (RTSA) vs hemiarthroplasty

Self‐reported shoulder function · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)
3 findings from 1 review