Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Medium income vs High income

Prevalence of untreated decay (% DT > 0) · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

In Australia, medium versus high income differed by 6.8 percentage points in prevalence of untreated decay.

4 findings from 1 review
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Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs standard local care

Major bleeding, requiring transfusion of packed red blood cells · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in major bleeding requiring transfusion of packed red blood cells compared with standard care (usual local haemostatic measures: gelatin sponge and…; GRADE not reported.

1 finding from 1 review

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs Placebo mouthwash

Number of thromboembolic complications · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…

The review found no eligible studies for this question.

1 finding from 1 review

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs standard local care

Number of participants with postoperative bleedings requiring intervention · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in number of participants with postoperative bleedings requiring… compared with standard care (usual local haemostatic measures: gelatin sponge and… (moderate certainty).

1 finding from 1 review

Low income vs High income

Mean number of decayed teeth (mean DT) · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

Across four countries, low versus high income differed by 0.44 decayed teeth in mean number of decayed teeth (random-effects meta-analysis; I2=76.4%).

5 findings from 1 review
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Orthodontic treatment without extraction of permanent teeth vs Orthodontic treatment involving extraction of permanent teeth

Gingival and TMJ symptoms · Children (80% aged <= 16 years) with a Class II division 2 malocclusion (deep bite and retroclined upper front teeth)

The review found no eligible studies for this question.

1 finding from 1 review

Fixed functional appliance (FORSUS FRD) vs Fixed functional appliance with mini-implants (FMI)

Final ANB · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Fixed functional appliance (FORSUS FRD) showed no clear difference in final ANB compared with fixed functional appliance with mini-implants (FMI); GRADE not reported.

1 finding from 1 review

Secondary education vs University education

Mean number of decayed teeth (mean DT) · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

In Canada, secondary versus university education differed by 0.7 decayed teeth in mean number of decayed teeth.

4 findings from 1 review
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Twin Block functional appliance vs Other functional appliances (Bionator, Herbst, R-appliance, Dynamax, Bite-Jumping)

Final ANB · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Twin Block functional appliance may leads to lower final ANB compared with other functional appliances (Bionator, Herbst, R-appliance, Dynamax,… (low certainty).

1 finding from 1 review

Orthodontic treatment without extraction of permanent teeth vs Orthodontic treatment involving extraction of permanent teeth

Duration of treatment · Children (80% aged <= 16 years) with a Class II division 2 malocclusion (deep bite and retroclined upper front teeth)

The review found no eligible studies for this question.

1 finding from 1 review

Post-secondary education vs University education

Prevalence of untreated decay (% DT > 0) · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

In Canada, post-secondary versus university education differed by 7.8 percentage points in prevalence of untreated decay.

4 findings from 1 review
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Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs Placebo mouthwash

Number of minor postoperative bleeding episodes · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in number of minor postoperative bleeding episodes compared with placebo (placebo solution/mouthwash); GRADE not reported.

1 finding from 1 review

Fixed functional appliance (FORSUS FRD) vs Fixed functional appliance with mini-implants (FMI)

Patient satisfaction · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Fixed functional appliance (FORSUS FRD) showed no clear difference in patient satisfaction compared with fixed functional appliance with mini-implants (FMI); GRADE not reported.

1 finding from 1 review

Orthodontic treatment without extraction of permanent teeth vs No treatment (or delayed treatment)

Cephalometric measurements (ANB change and front teeth inclination changes) · Children (80% aged <= 16 years) with a Class II division 2 malocclusion (deep bite and retroclined upper front teeth)

The review found no eligible studies for this question.

1 finding from 1 review

Extraction of a maxillary first permanent molar vs Extraction of a mandibular first permanent molar

Spontaneous space closure · Children aged 5 to 15 years undergoing first permanent molar extraction

Spontaneous post-extraction space closure did not differ significantly between the maxilla and mandible (pooled OR 2.06, 95% CI 0.46 to 9.28; 3 studies; I2 = 72%); ungraded.

1 finding from 1 review

Post-secondary education vs University education

Prevalence of fair/poor self-rated oral health · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

In Canada, post-secondary versus university education differed by 2.4 percentage points in prevalence of fair/poor self-rated oral health.

4 findings from 1 review
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Medium income vs High income

Mean number of decayed teeth (mean DT) · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

In United States, medium versus high income differed by 0.1 decayed teeth in mean number of decayed teeth.

4 findings from 1 review
Show 1 more finding