Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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Endovenous laser ablation (EVLA) vs foam sclerotherapy

Technical success · people with GSV incompetence

Endovenous laser ablation (EVLA) showed no clear difference in technical success (< 5 years) compared with ultrasound‐guided foam sclerotherapy (UGFS) (low certainty).

2 findings from 1 review

Fluoexetine vs placebo

Change in weight (kg) · People who have quit smoking

Fluoexetine showed no clear difference in mean weight change (kg) at end of treatment compared with placebo (low certainty).

2 findings from 1 review