Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
In prospective cohorts, adults with 11-16 teeth had a higher cumulative incidence of ACVD-related events than adults with 25-32 teeth (RR 2.27, 95% CI 1.55 to 3.32; 4 cohort studies, I2=87%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
1 finding from 1 review
All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
In prospective cohorts, the multivariable-adjusted HR for all-cause mortality in edentulous adults (0 teeth) vs adults with 1-32 teeth was 1.30 (95% CI 1.21 to 1.40; 7 studies, I2=20%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
4 findings from 1 review
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Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
In prospective cohorts, adults with 17-24 teeth had a higher cumulative incidence of ACVD-related events than adults with 25-32 teeth (RR 1.73, 95% CI 1.22 to 2.45; 4 cohort studies, I2=87%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
1 finding from 1 review
All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
In prospective cohorts, the crude HR for all-cause mortality in adults with 0-19 teeth vs adults with 20-32 teeth was 2.47 (95% CI 2.40 to 2.54; 2 studies, I2=0%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
4 findings from 1 review
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All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
In prospective cohorts, adults with 1-19 teeth had a higher cumulative incidence of all-cause mortality than adults with 20-32 teeth (RR 1.76, 95% CI 1.41 to 2.19; 8 cohort studies, I2=94%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
1 finding from 1 review
Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
In prospective cohorts, the multivariable-adjusted HR for ACVD-related events in edentulous adults (0 teeth) vs adults with 1-32 teeth was 1.21 (95% CI 1.07 to 1.36; 5 studies, I2=35%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
4 findings from 1 review
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Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
In prospective cohorts, the crude HR for ACVD-related events in adults with 0-19 teeth vs adults with 20-32 teeth was 2.27 (95% CI 1.50 to 3.43; 1 study, I2 not applicable (single study)); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
4 findings from 1 review
Show 1 more finding
Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
In prospective cohorts, edentulous adults (0 teeth) had a higher cumulative incidence of ACVD-related events than adults with 20-32 teeth (RR 2.65, 95% CI 1.77 to 3.98; 2 cohort studies, I2=60%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
1 finding from 1 review
Treatment failure (escalation of respiratory therapy to NIV, NIPPV or invasive ventilation) Measured up to 28 days · adults in the ICU, requiring respiratory support
HFNC may leads to lower treatment failure (escalation of respiratory therapy to NIV, NIPPV… compared with standard oxygen therapy (low certainty).
1 finding from 1 review
Adverse events ‐ pneumonia · adults in the ICU, requiring respiratory support
It is very uncertain whether HFNC changes adverse events Respiratory infection (pneumonia) compared with NIPPV or NIV (very low certainty).
1 finding from 1 review
Barotrauma (pneumothorax) · adults in the ICU, requiring respiratory support
HFNC showed no clear difference in barotrauma (pneumothorax) compared with NIPPV or NIV (low certainty).
1 finding from 1 review
Nasal mucosa or skin trauma · adults in the ICU, requiring respiratory support
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Duration of ICU stay · adults in the ICU, requiring respiratory support
1 finding from 1 review
Respiratory effects: PaO2/FiO2 ratio up to 24 hours after initiation of therapy · adults in the ICU, requiring respiratory support
1 finding from 1 review
In‐hospital mortality (up to 90 days; included studies reported in‐hospital mortality, and mortality up to 28 days and up to ICU discharge) · adults in the ICU, requiring respiratory support
HFNC showed no clear difference in in‐hospital mortality (up to 90 days; included studies reported… compared with standard oxygen therapy (moderate certainty).
1 finding from 1 review
Adverse events Respiratory infection (pneumonia) Nasal mucosa or skin trauma · adults in the ICU, requiring respiratory support
HFNC showed no clear difference in adverse events Respiratory infection (pneumonia) Nasal mucosa or… compared with standard oxygen therapy (moderate certainty).
1 finding from 1 review
Duration of ICU stay · adults in the ICU, requiring respiratory support
1 finding from 1 review
Respiratory effects: PaO2/FiO2 ratio up to 24 hours after initiation of therapy · adults in the ICU, requiring respiratory support
1 finding from 1 review
Treatment failure (escalation of respiratory therapy to NIV, NIPPV or invasive ventilation) Measured up to 28 days · adults in the ICU, requiring respiratory support
HFNC showed no clear difference in treatment failure (escalation of respiratory therapy to NIV, NIPPV… compared with NIPPV or NIV (low certainty).
1 finding from 1 review
In‐hospital mortality (up to 90 days; included studies reported in‐hospital mortality, and mortality up to 28 days and up to ICU discharge) · adults in the ICU, requiring respiratory support
HFNC showed no clear difference in in‐hospital mortality (up to 90 days; included studies reported… compared with NIPPV or NIV (low certainty).
1 finding from 1 review