Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

311 questions · 323 findings · 30 reviews

No studies found 47 · 14.6%GRADE not reported 21 · 6.5%Very low 91 · 28.2%Low 65 · 20.1%Moderate 82 · 25.4%High 17 · 5.3%

ZOTEPINE vs REMOXIPRIDE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · patients with schizophrenia

ZOTEPINE showed no clear difference in adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with REMOXIPRIDE (low certainty).

1 finding from 1 review

ZOTEPINE vs CLOZAPINE

Global state: No clinically important response (as defined by the original studies) · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes global state: No clinically important response (as defined by the… compared with CLOZAPINE (very low certainty).

1 finding from 1 review

ZOTEPINE vs CLOZAPINE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with CLOZAPINE (very low certainty).

1 finding from 1 review

ZOTEPINE vs RISPERIDONE

Adverse effects: Extrapyramidal effects ‐ use of antiparkinson medication ‐ vs 4mg risperidone · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (very low certainty).

1 finding from 1 review

ZOTEPINE vs RISPERIDONE

Adverse effects: Extrapyramidal effects ‐ use of antiparkinson medication ‐ vs 8mg risperidone · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (very low certainty).

1 finding from 1 review