Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

416 questions · 426 findings · 56 reviews

No studies found 109 · 25.6%GRADE not reported 23 · 5.4%Very low 109 · 25.6%Low 106 · 24.9%Moderate 64 · 15%High 15 · 3.5%

Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone

Risk of necrotising enterocolitis stage ≥ 2 · feed interruption while monitoring gastric residual

Summary of findings table ‐ Quality and volume of gastric residual showed no clear difference in risk of necrotising enterocolitis stage ≥ 2 compared with quality of gastric residual alone (low certainty).

1 finding from 1 review

Summary of findings table for the comparison of 'intensified patient care' vs usual care

Adherence to antipsychotic medication: number of missed doses, average endpoint data, short term (up to 6 months) · People receiving lipid‐lowering medications

Summary of findings table for the comparison of 'intensified patient… probably leads to higher medication adherence at ≤ 6 months compared with 'usual care' (moderate certainty).

1 finding from 1 review

Summary of findings table for the comparison of 'intensified patient care' vs usual care

Medication adherence (dichotomous) · People receiving lipid‐lowering medications

Summary of findings table for the comparison of 'intensified patient… leads to higher medication adherence at > 6 months compared with 'usual care' (high certainty).

1 finding from 1 review

Summary of findings for IV terbutaline vs IV nitroglycerin

Umbilical artery pH < 7.0 · women with non‐reassuring FHR tracing during labour or induction of labour

It is very uncertain whether summary of findings for IV terbutaline changes umbilical artery pH < 7.0 compared with IV nitroglycerin (very low certainty).

1 finding from 1 review

Summary of findings for IV terbutaline vs IV nitroglycerin

Successful intrauterine fetal resuscitation · women with non‐reassuring FHR tracing during labour or induction of labour

Summary of findings for IV terbutaline showed no clear difference in successful intrauterine fetal resuscitation compared with IV nitroglycerin (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Perinatal death or severe morbidity · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Fetal or neonatal mortality · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline showed no clear difference in fetal or neonatal mortality compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Apgar score less than 7 at 5 minutes · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline showed no clear difference in 5‐minute Apgar score < 7 compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Low umbilical artery pH (< 7.2 or as defined by trial authors) · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline showed no clear difference in umbilical artery pH < 7.2 compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Abnormal FHR as defined by trial authors (FHR tracing not improved) · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline probably leads to lower FHR tracing not improved compared with no tocolytic agent, whilst awaiting emergency delivery (moderate certainty).

1 finding from 1 review