Propyl betaine and polihexanide vs Normal saline
Change in ulcer size · participants with chronic leg ulcers
1 finding from 1 review
- no estimate extracted1 study · 38 participantsVery low
Findings
What do systematic reviews say?
508 questions · 529 findings · 58 reviews
No studies found 191 · 36.1%GRADE not reported 49 · 9.3%Very low 143 · 27%Low 92 · 17.4%Moderate 51 · 9.6%High 3 · 0.6%
Propyl betaine and polihexanide vs Normal saline
Procedural pain · participants with chronic leg ulcers
1 finding from 1 review
- no estimate extracted1 study · 38 participantsVery low
Propyl betaine and polihexanide vs Normal saline
Costs · participants with chronic leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Polyhexamethylene biguanide (PHMB) vs Normal saline
Number of wounds healed · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Propyl betaine and polihexanide vs Normal saline
Health related quality of life · participants with chronic leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Propyl betaine and polihexanide vs Normal saline
Adverse events after 4 weeks of · participants with chronic leg ulcers
1 finding from 1 review
- no estimate extracted1 study · 38 participantsVery low
Polyhexamethylene biguanide (PHMB) vs Normal saline
Change in ulcer size · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Polyhexamethylene biguanide (PHMB) vs Normal saline
Pain · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Polyhexamethylene biguanide (PHMB) vs Normal saline
Costs · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Polyhexamethylene biguanide (PHMB) vs Normal saline
Health related quality of life · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Polyhexamethylene biguanide (PHMB) vs Normal saline
Adverse events · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to the patient or HCW before and/or after an AGP vs No treatment or saline or water
Changes in microbiome in oral cavity, nasal cavity, oro- or nasopharynx · Patients without suspected or confirmed COVID-19 infection undergoing aerosol-generating procedures (AGPs), and the healthcare workers…
The review found no eligible studies for this question.
1 finding from 1 review
- Antimicrobial mouthwashes (gargling) and nasal sprays to protect healthcare workers when undertaking… 2020 · Cochrane All outcomesNo data available (no included studies)Studies not reportedNo studies found
Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to the patient or HCW before and/or after an AGP vs No treatment or saline or water
Other adverse events (allergy, irritation/burning of nasal, oral or oropharyngeal mucosa, long-term staining of mucous membranes or teeth, accidental ingestion) · Patients without suspected or confirmed COVID-19 infection undergoing aerosol-generating procedures (AGPs), and the healthcare workers…
The review found no eligible studies for this question.
1 finding from 1 review
- Antimicrobial mouthwashes (gargling) and nasal sprays to protect healthcare workers when undertaking… 2020 · Cochrane All outcomesNo data available (no included studies)Studies not reportedNo studies found
Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to healthcare workers, with or without the same intervention given to the patients with COVID-19 vs No treatment or saline or water
Anosmia (or disturbance in sense of smell) · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
- Use of antimicrobial mouthwashes (gargling) and nasal sprays by healthcare workers to protect them when treating… 2020 · Cochrane All outcomesMinimum 2 weeksNo data available (no included studies)0 studiesNo studies found
Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to healthcare workers, with or without the same intervention given to the patients with COVID-19 vs No treatment or saline or water
Viral content of aerosol · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
- Use of antimicrobial mouthwashes (gargling) and nasal sprays by healthcare workers to protect them when treating… 2020 · Cochrane All outcomesNo data available (no included studies)0 studiesNo studies found
Triclosan rinse vs Saline rinse
Duration of ICU stay · Critically ill patients receiving mechanical ventilation in ICU
Triclosan rinse led to lower duration of ICU stay compared with saline rinse; GRADE not reported.
1 finding from 1 review
- Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomesMD -4.97 [-5.55, -4.39]1 study · 324 participantsGRADE not reported
Hydrogen peroxide vs Normal saline
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
- Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomesHydrogen peroxide versus normal saline (Nobahar 2016): a reduction in VAP was found; single study, not replicated, interpret with caution.1 studyGRADE not reported
Povidone iodine rinse vs Saline rinse or placebo
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Povidone iodine rinse showed no clear difference in mortality compared with saline rinse or placebo; GRADE not reported.
1 finding from 1 review
- Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomesRR 1.00 [0.66, 1.50]2 studies · 217 participantsGRADE not reported
Triclosan rinse vs Saline rinse
Duration of mechanical ventilation · Critically ill patients receiving mechanical ventilation in ICU
Triclosan rinse led to lower duration of mechanical ventilation compared with saline rinse; GRADE not reported.
1 finding from 1 review
- Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomesMD -5.24 [-5.64, -4.84]1 study · 324 participantsGRADE not reported
Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment or saline or water
COVID-19 viral content of aerosol (when present) · Patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
- Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed COVID‐19… 2020 · Cochrane All outcomesNo data available (no included studies)0 studiesNo studies found