Findings

What do systematic reviews say?

461 questions · 472 findings · 42 reviews · Neuromuscular

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No studies found 93 · 19.7%GRADE not reported 81 · 17.2%Very low 99 · 21%Low 103 · 21.8%Moderate 75 · 15.9%High 21 · 4.4%

Quinine vs placebo

Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 666 participants
Moderate

Quinine vs placebo

Major adverse events · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
18 studies · 1103 participants
Moderate

Quinine vs placebo

Minor adverse events · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 969 participants
Moderate

IVIg vs placebo

Activity limitations · people with postpolio syndrome

2 findings from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 185 participants
Moderate
Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 91 participants
Low

Amantadine vs placebo

Activity limitations ‐ not measured · people with postpolio syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amantadine vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
GRADE not reported

Prednisone vs placebo

Activity limitations ‐ not measured · people with postpolio syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prednisone vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
GRADE not reported

Static magnetic fields vs placebo

Activity limitations ‐ not measured · people with postpolio syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Static magnetic fields vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
GRADE not reported

IVIg vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 212 participants
GRADE not reported

Modafinil vs placebo

Activity limitations · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
High

Modafinil vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 50 participants
GRADE not reported

Pyridostigmine vs placebo

Change in activity limitations · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 124 participants
Moderate

Pyridostigmine vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 193 participants
GRADE not reported

Gabapentin vs placebo

Participant‐reported pain relief of 50% or greater · patients with pain in Guillain‐Barré syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for pain in Guillain‐Barré syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Carbamazepine vs placebo

Rescue analgesic consumption · patients with pain in Guillain‐Barré syndrome

It is very uncertain whether carbamazepine changes rescue analgesic consumption compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological treatment for pain in Guillain‐Barré syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Summary of findings table ‐ Methylprednisolone vs placebo

Participant‐reported pain relief of 50% or greater · patients with pain in Guillain‐Barré syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for pain in Guillain‐Barré syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Methylprednisolone vs placebo

Number of participants with pain after 4 weeks · patients with pain in Guillain‐Barré syndrome

Methylprednisolone showed no clear difference in number of participants with pain after 4 weeks compared with placebo (low certainty).

1 finding from 1 review

Pharmacological treatment for pain in Guillain‐Barré syndrome 2015 · Cochrane Headline outcomes only
RR 0.89 [0.68, 1.16]
1 study · 223 participants
Low

Summary of findings table ‐ Methylprednisolone vs placebo

Number of participants with decreased pain after 4 weeks · patients with pain in Guillain‐Barré syndrome

Methylprednisolone showed no clear difference in number of participants with decreased pain after 4 weeks compared with placebo (low certainty).

1 finding from 1 review

Pharmacological treatment for pain in Guillain‐Barré syndrome 2015 · Cochrane Headline outcomes only
RR 0.95 [0.63, 1.42]
1 study · 223 participants
Low