Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

678 questions · 854 findings · 51 reviews · Dental caries

No studies found 38 · 4.4%GRADE not reported 675 · 79%Very low 61 · 7.1%Low 47 · 5.5%Moderate 32 · 3.7%High 1 · 0.1%

Vitapex (calcium hydroxide/iodoform) vs ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) led to higher radiological failure compared with ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product); GRADE not reported.

1 finding from 1 review

Ferric sulphate (FS) + mineral trioxide aggregate (MTA) vs Ferric sulphate (FS)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    mean 22 months
    Assessed pain, soft tissue, mobility, adjacent tissue inflammation, radiolucency, root resorption, pulp canal obliteration (Doyle 2010); no clinical/radiological failure outcome; no significant differences
    1 study · 135 participants
    GRADE not reported

Self-etch adhesive + acetone-based total-etch adhesive vs Acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Diode laser vs Formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Diode laser showed no clear difference in radiological failure compared with formocresol (FC); GRADE not reported.

1 finding from 1 review

Electrofulguration + calcium hydroxide (CH) vs Electrofulguration + zinc oxide and eugenol (ZOE)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Electrofulguration + calcium hydroxide (CH) showed no clear difference in clinical failure compared with electrofulguration + zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review